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神經叢蛋白B2抗體

英文名稱 Plexin B2
中文名稱 神經叢蛋白B2抗體
別    名 KIAA0315; Plexin B2; PlexinB2; Plexin-B2; MM1; PLXN B2; PLXNB2.
  
說 明 書 0.1ml  0.2ml  
研究領域 細胞生物  神經生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Horse, 
產品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 203kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Plexin B2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the
PubMed PubMed
產品介紹 background:
Plexins are a family of large, transmembrane receptors for multiple classes of semaphorins in vertebrates. They are widely expressed, and regions of their extracellular domain are homologus to both scatter factor receptors and semaphorin domains. Plexins may act as semaphorin receptors alone or in combination with neuropilins. Plexins are divided into four subfamilies designated plexin-A, -B, -C, and -D. Plexin-B1 and -B2 are both receptors for Sema4D, which stimulates axonal outgrowth of embryonic dorsal root ganglion neurons. . Plexin-B3 binds to Sema5A, which controls axon guidance and can initiate the intracellular signaling of the hepatocyte growth factor/scatter factor receptor Met.

Function:
Plexin B2 is a transmembrane receptor for the class 4 semaphorin, SEMA4D. This receptor has key roles in RHOA activation and subsequent changes of the actin cytoskeleton, axon guidance, invasive growth and cell migration.

Subunit:
Monomer, and heterodimer with PLXNB1. Interacts with SEMA4C, SEMA4D and SEMA4G (By similarity). Binds MET, ARHGEF11 and ARHGEF12. May also interact with MST1R. 

Subcellular Location:
Membrane; single-pass type I membrane protein.

Similarity:
Belongs to the plexin family. 
Contains 3 IPT/TIG domains. 
Contains 1 Sema domain. 

Database links:
UniProtKB/Swiss-Prot: O15031.3xy-11928R    PTBP2核糖核酸結合蛋白2抗體
xy-4888R    Phospho-PPAR Gamma (ser273)磷酸化過氧化酶活化增生受體γ抗體 PPARγ
xy-11681R    Presenilin 1 + 2早老素蛋白1+2抗體
xy-10043M    PRRSV豬藍耳病病毒抗體
xy-6472R    Phospholipase C beta 2磷酯酶Cβ2抗體
xy-8300R    Peroxiredoxin 2硫氧還蛋白過氧化物酶Ⅱ/巰基抗氧化蛋白抗體
xy-6423R    PI3 Kinase p110 beta磷脂酰肌醇激酶（PI3Kβ）抗體
xy-6918R    PPAPDC3磷脂酸磷酸酶2結構域3抗體
xy-6904R    PRC1胞質分裂調控蛋白1抗體
xy-6419R    phospho-PP2A alpha+beta(Tyr307)磷酸化蛋白磷酸酶2A（PP2Aα）抗體
xy-8062R    PLEKHM1石骨癥相關蛋白PLEKHM1抗體
xy-8063R    PLEKHM2血小板白細胞C激酶底物同源結構域M2抗體
xy-8064R    PLEKHM3血小板白細胞C激酶底物同源結構域M3抗體
xy-2138R    PARP多腺苷二磷酸多聚酶抗體(N端)
xy-11471R    PTPRD酪氨酸磷酸酶PTPδ抗體 蛋白酪氨酸磷酸酶D受體抗體
xy-11123R    PCDHA10/CNRN8鈣粘蛋白相關神經受體8抗體
xy-11112R    PCDH18原鈣粘附蛋白18抗體
xy-11113R    PCDH20原鈣粘附蛋白20抗體
xy-11114R    PCDH8原鈣粘附蛋白8抗體
xy-6371R    Protamine 2魚精蛋白2抗體
xy-6853R    PIWIL4piwi樣4蛋白抗體
xy-6348R    PIWIL3piwi樣3蛋白抗體
xy-4743R    PRRSV豬繁殖與呼吸綜合征/豬藍耳病病毒抗體
xy-6847R    PDCD10凋亡相關蛋白10抗體
xy-7595R    PPM1F鈣調蛋白依賴性蛋白激酶磷酸酶抗體
xy-4852R    PIM3絲氨酸/蘇氨酸蛋白激酶PIM3抗體
xy-6992R    PRMT5組蛋白精氨酸甲基轉移酶5抗體
xy-11107R    PCDH11X原鈣粘附蛋白11X抗體
xy-11108R    PCDH11Y原鈣粘附蛋白11Y抗體
xy-11109R    PCDH12原鈣粘附蛋白12/血管內皮鈣粘蛋白2抗體
xy-11110R    PCDH17原鈣粘附蛋白17抗體
xy-11111R    PCDH1原鈣粘附蛋白1抗體