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核糖核酸結(jié)合蛋白1抗體

英文名稱 PTBP1
中文名稱 核糖核酸結(jié)合蛋白1抗體
別    名 Heterogeneous nuclear ribonucleoprotein I; Heterogeneous Nuclear Ribonucleoprotein Polypeptide I; hnRNP I; HNRNPI; HNRPI; MGC10830; MGC8461; Polypyrimidine Tract Binding Protein 1; Polypyrimidine tract binding protein; Polypyrimidine tract-binding protein 1; pPTB; PTB 1; PTB 2; PTB 3; PTB 4; PTB; PTB T; PTB1; PTB2; PTB3; PTB4; PTBP 1; PTBP1; PTBP1_HUMAN; PTBT; RNA Binding Protein; 57 kDa RNA binding protein PPTB 1; 57 kDa RNA binding protein PPTB1; 57 kDa RNA-binding protein PPTB-1.
  
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 染色質(zhì)和核信號(hào)  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PTBP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.

Function:
Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. xy-3744R    Phospho-Paxillin(Tyr31)磷酸化樁蛋白Paxillin抗體
xy-3806R    PGP9.5神經(jīng)細(xì)胞胞漿蛋白9.5抗體（蛋白基因產(chǎn)物9.5）
xy-4024R    phospho-PKA beta(Ser338)磷酸化蛋白激酶Aβ抗體
xy-3963R    PKA R2蛋白激酶A受體2α亞基抗體
xy-4022R    phospho-PKA R2 (Ser96)磷酸化蛋白激酶A受體2α亞基抗體
xy-3964R    PKA gamma蛋白激酶Aγ抗體
xy-3965R    PKA regulatory subunit I beta蛋白激酶受體相關(guān)1β抗體
xy-6466R    PRDM1B淋巴細(xì)胞誘導(dǎo)成熟蛋白1抗體
xy-5179R    phospho-PTPRA(Tyr798)磷酸化酪氨酸磷酸酶α抗體
xy-3969R    PRKAR1蛋白激酶A調(diào)節(jié)亞基a1抗體
xy-5175R    phospho-PTPRA (Ser180)磷酸化酪氨酸磷酸酶α抗體
xy-9039R    PDZD5APDZ結(jié)構(gòu)域PDZK5A蛋白抗體
xy-5423R    PPAP2A磷酸脂磷酸水解酶1抗體
xy-4592R    P14ARF抑癌基因p16/p14/P19抗體
xy-9187R    PTPH1蛋白酪氨酸磷酸酶H1抗體
xy-5587R    phospho-PI 3 Kinase p110 delta (Tyr524)磷酸化磷脂酰肌醇激酶催化亞單位D抗體
xy-5643R    phospho-RAD9(Ser277)磷酸化細(xì)胞周期檢查控制蛋白質(zhì)抗體
xy-7128R    Perforin穿孔素抗體
xy-13674R    PALM3PALM3抗體
xy-5107R    PON1芳香酯酶1(對(duì)氧磷酶)抗體
xy-5108R    PNPO磷酸吡哆醇氧化酶抗體
xy-5565R    phospho-PRKCB(Ser660)磷酸化蛋白激酶C抗體
xy-5566R    phospho-PRKCB(Ser642)磷酸化蛋白激酶C抗體
xy-5567R    Phospho-PTEN(Ser385)磷酸化腫瘤抑制基因PTEN抗體
xy-5570R    phospho-PI3KCA(Tyr317)磷酸化磷脂酰肌醇激酶催化亞單位A抗體
xy-5571R    phospho-PIK3R1(Tyr467)磷酸化磷脂酰肌醇激酶抗體
xy-5572R    phospho-PIK3R1(Tyr556)磷酸化磷脂酰肌醇激酶抗體
xy-5573R    phospho-PRKCA(Ser657+Tyr658)磷酸化蛋白激酶C抗體
xy-5574R    phospho-PRKCA(Thr637)磷酸化蛋白激酶C抗體
xy-5575R    phospho-AMPK alpha 2 (Ser173)磷酸化腺苷單磷酸活化蛋白激酶α2抗體
xy-4158R    SHP1蛋白酪氨酸磷酸酶1C抗體
xy-5577R    phospho-PTPN6(Tyr536)磷酸化蛋白酪氨酸磷酸酶1C抗體