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血小板源性生長(zhǎng)因子A抗體

英文名稱(chēng) PDGF-A
中文名稱(chēng) 血小板源性生長(zhǎng)因子A抗體
別    名 Plaet–dirived growth factor–1; PDGFA; PDGF AA; PDGF-AA; PDGF A chain; PDGF subunit A; PDGF-1; PDGF1; PDGFA; PDGFA_HUMAN; Plaet derived growth factor A chain precursor; Plaet derived growth factor alpha polypeptide; Plaet-derived growth factor A chain; Plaet-derived growth factor alpha polypeptide; Plaet-derived growth factor subunit A.
 
說(shuō) 明 書(shū) 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  免疫學(xué)  神經(jīng)生物學(xué)  生長(zhǎng)因子和激素  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human PDGF-A
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

產(chǎn)品介紹 background:
Plaet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by plaets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heal the wound. Antiparallel disulfide-linked dimer of nonidentical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. The long form contains a basic insert which acts as a cell retention signal. A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor. It belongs to the PDGF/VEGF growth factor family.

Function:
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB.xy-3709R    phospho-P53 (Ser9)磷酸化腫瘤抑制基因P53抗體
xy-3710R    phospho-P53(Thr18)磷酸化腫瘤抑制基因P53抗體
xy-3711R    phospho-P53(Thr81)磷酸化腫瘤抑制基因P53抗體
xy-6147R    p73 alphap53相關(guān)蛋白P73α抗體
xy-6146R    p53 DINP1p53誘導(dǎo)核蛋白1抗體
xy-2944R    plant lectin B4植物凝集素IB4
xy-6143R    PIG3p53誘導(dǎo)蛋白3抗體
xy-6144R    PRMT4組蛋白精氨酸甲基轉(zhuǎn)移酶CARM1抗體
xy-5433R    PPAP2C磷酸脂磷酸水解酶2抗體
xy-4184R    p107視網(wǎng)膜母細(xì)胞瘤樣蛋白p107抗體
xy-5597R    phospho-P53(Ser376)磷酸化腫瘤抑制基因P53抗體
xy-6061R    PIGR多聚免疫球蛋白受體抗體
xy-11135R    PCDHB16原鈣粘蛋白16抗體
xy-6062R    PRDM2鋅指蛋白R(shí)IZ1抗體
xy-6063R    PRMT6組蛋白精氨酸甲基轉(zhuǎn)移酶6抗體
xy-6064R    PRSS8絲氨酸蛋白酶8抗體
xy-1652R    phospho-PAK1/2/3(Thr423)磷酸化p21激活激酶1/2/3抗體
xy-6051R    Prostaglandin dehydrogenase 1前列腺素脫氫酶1抗體
xy-2505R    phospho-PRKCZ(Thr500)磷酸化蛋白激酶C(T500)抗體
xy-1650R    phospho-P53(Ser392)磷酸化腫瘤抑制基因P53抗體
xy-1653R    phospho-PAK1 (Ser144)磷酸化p21激活激酶1抗體
xy-1654R    phospho-PAK2 (Ser141)磷酸化p21激活激酶2抗體
xy-1655R    phospho-PAK3 (Ser139)磷酸化p21激活激酶3抗體
xy-1651R    phospho-PAK1+PAK2+PAK3 (Ser141)磷酸化p21激活激酶1/2/3抗體
xy-1656R    phospho-P70 S6 Kinase beta (Thr228)磷酸化核糖體S6蛋白激酶抗體
xy-2638R    PROK1/PRK1/EG-VEGF內(nèi)分泌腺衍生血管內(nèi)皮生長(zhǎng)因子抗體
xy-2469R    PERK蛋白激酶樣內(nèi)質(zhì)網(wǎng)激酶抗體
xy-2899R    PMSA前列腺特異膜抗原抗體
xy-0128R    PI3 kinase p85 alpha subunit磷脂酰肌醇激酶抗體
xy-0234R    PLGF胎盤(pán)生長(zhǎng)因子抗體
xy-0520R    PKA alpha + beta蛋白激酶A抗體
xy-0267R    PKC beta 1 + 2蛋白激酶C beta 1/2抗體