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詳細(xì)介紹

概述
描述	Recombinant Human Alkaline Phosphatase is produced by our Mammalian expression system and the target gene encoding Ile23-Asp506 is expressed with a 6His tag at the C-terminus.
別名	Alkaline phosphatase, placental type, also known as Alkaline phosphatase Regan isozyme, Placental alkaline phosphatase 1, ALPP and PLAP, belongs to the alkaline phosphatase family.
形態(tài)	Supplied as a 0.2 μm filtered solution of PBS, pH 7.4 .
來源	Human Cells
氨基酸序列	IIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGP EIPLAMDRFPYVALSKTYNVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVI SVMNRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMD IDVILGGGRKYMFRMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRMQASLDP SVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAY RALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTV LLYGNGPGYVLKDGARPDVTESESGSPEYRSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQ TFIAHVMAFAACLEPYTACDLAPPAGTTDVDHHHHHH
內(nèi)毒素水平	Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Accession #	P05187

性能
背景	ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a role in a number of processes including cell signaling, long-term potentiation, and cell adhesion, however, the best known and most commonly studied role is implicated in Alzheimer's research.
保存方法	Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
純度	Greater than 95% as determined by reducing SDS-PAGE.