PBL Assay Science人IFN-Omega增強(qiáng)相容性復(fù)合物I類抗原的表達(dá)

人IFN-Omega在體外抑制多種腫瘤細(xì)胞系的增殖，刺激自然殺傷細(xì)胞活性，增強(qiáng)主要組織相容性復(fù)合物I類抗原的表達(dá)。

PBL Assay Science/艾美捷人IFN-Omega（PBL-11395-1）規(guī)格：

配方 以冷凍形式提供載體蛋白

分子量 20 千達(dá)

源 在大腸桿菌中表達(dá)的重組胡-IFN-ω

純度 > 95% 通過考馬斯藍(lán)

內(nèi)毒素水平 < 1 EU/μg 染色的 SDS-PAGE

生物 活性 使用細(xì)胞病變抑制測(cè)定法對(duì)伴有腦心肌炎病毒 （EMCV） 的人肺癌細(xì)胞系 A549 進(jìn)行測(cè)量

存儲(chǔ) 為了保持全部活性，請(qǐng)儲(chǔ)存在 -70°C 或以下，避免反復(fù)凍融循環(huán)

同義詞 干擾素-ω

PBL Assay Science 人IFN-Omega引用文獻(xiàn)：

Li, Y.,et al., (2023), "An Extracellular Humanized IFNAR Immunocompetent Mouse Model for Analyses of Human Interferon Alpha and Subtypes", Emerg Microbes Infect. 2287681. PMID: 37994664, DOI: 10.1080/22221751.2023.2287681 (link)

Richez, Christophe, et al. (2009). TLR4 Ligands Induce IFN-alpha Production by Mouse Conventional Dendritic Cells and Human Monocytes after IFN-beta Priming. Journal of Immunology, 10 pgs. PMID: 19124725.

Kang, Dong-Chul, et al. (2004). Expression Analysis and Genomic Characterization of Human Melanoma Differentiation Associated Gene-5, mda-5: a Novel Type I Interferon-Responsive Apoptosis-Inducing Gene. Oncogene, 12 pgs. PMID: 14676839.

Qu, C, et al. (2003). Autocrine type I IFN and contact with endothelium promote the presentation of influenza A virus by monocyte-derived APC. Journal of Immunology, 10 pgs. PMID: 12517968.

Adolf, Gunther (1990). Monoclonal antibodies and enzyme immunoassays specific for human interferon (IFN) omega 1: evidence that IFN-omega 1 is a component of human leukocyte IFN. Virology, 8 pgs. PMID: 1691561.