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目錄:上海貝博生物科技有限公司>>Primary Antibodies>> Caldesmon (phospho Ser759) rabbit pAb

Caldesmon (phospho Ser759) rabbit pAb
  • Caldesmon (phospho Ser759) rabbit pAb
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更新時(shí)間:2025-01-12 18:49:28瀏覽次數(shù):116評(píng)價(jià)

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SourceRabbitApplicationsIHC,ELISAReactivityHuman,Mouse,RatDilutionIHC:1:100-1:300
  • Source

    Rabbit

  • Applications

    IHC,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-Caldesmon (S759) Polyclonal Antibody detects endogenous levels of Caldesmon protein only when phosphorylated at S759.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser759. AA range:725-774

  • Uniprot No

    Q05682

  • Alternative names

    CALD1; CAD; CDM; Caldesmon; CDM

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    caldesmon 1(CALD1) Homo sapiens This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

  • Other

    CALD1, Caldesmon

  • Mol.Wt (Da)

    high molecular weight (predominantly in smooth muscles) (120-150 KD) and a low molecular weight (60-90KD)

  • Concentration

    1 mg/ml

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