Recombinant human VPS4a protein   

hVPS4; SKD1; SKD1 homolog; SKD2; Vacuolar protein sorting 4 homolog A; vacuolar sorting protein 4; VPS4.    

濃度：1mg/ ml

來源：Recombinant Human

純度：≥95% SDS-PAGE

表達(dá)系統(tǒng)：Wheat germ

標(biāo)簽：GST tag N-Terminus

蛋白長(zhǎng)度：Full length protein

內(nèi)毒素水平：<1.000 Eu/µg

純化方法：HPLC

應(yīng)用：SDS-PAGE，Western blot，ELISA

Biological activity,immunology research

保存：-20℃

保質(zhì)期：1年

Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Involved in cytokinesis.

產(chǎn)品名稱：Rabbit Anti-VPS4a protein antibody

Rabbit Anti-VPS4a protein 

別名：hVPS4; SKD1; SKD1 homolog; SKD2; Vacuolar protein sorting 4 homolog A; vacuolar sorting protein 4; VPS4.               

來源：Rabbit

克隆類型：Polyclonal

濃度：1mg/ml

亞型：IgG

反應(yīng)：Human,Mouse (predicted: Rat,Rabbit,Pig,Dog)

應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500  Flow-Cyt=3ug/Test

理論分子量：48 kDa

免疫原：KLH conjugated synthetic peptide derived from human VPS4a protein

保存：-20℃
保質(zhì)期：1年

產(chǎn)品名稱：Anti-VPS4a protein antibody

Mouse Anti-VPS4a protein

別名：hVPS4; SKD1; SKD1 homolog; SKD2; Vacuolar protein sorting 4 homolog A; vacuolar sorting protein 4; VPS4.                 

來源：Mouse

克隆類型：Monoclonal

濃度：1mg/ml

亞型：IgG

反應(yīng)：Human

應(yīng)用：WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500 Flow-Cyt=3ug/Test

反應(yīng):  Human

理論分子量：48 kDa

免疫原：KLH conjugated synthetic peptide derived from human VPS4a protein

保存：-20℃
保質(zhì)期：1年

Involved in intracellular protein transport probably out of a prevacuolar endosomal compartment. May be involved in the release of components of the bilayered coat from the endosomal membrane. The association with ESCRT-III complex mediates the ATP-dependent disassembly of the ESCRT-III complex. In case of infection, the HIV-1 virus takes advantage of it for budding and exocytic cargos of viral proteins.