中文名稱(chēng)：DBCO-NHS

英文名稱(chēng)：Dibenzocyclooctyne-N-hydroxysuccinimidyl ester

英文別名：Dibenzocyclooctyne-N-hydroxysuccinimidyl ester;

2,5-dioxopyrrolidin-1-yl 4-(didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate;

DBCO-NHS ester;2,5-dioxopyrrolidin-1-yl 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoate;DBCO-succinyl N-hydroxysuccinimidyl ester;

CAS號(hào)：1353016-71-3

分子式：C23H18N2O5

分子量：402.39900

質(zhì)量：402.12200

PSA：83.99000

LogP：2.32330

結(jié)構(gòu)式：

Description:
DBCO (Dibenzocyclooctyne) is a cycloalkyne that can reacts with azides via strain-promoted 1,3-dipolar cycloaddition in aqueous solution, a bioorthogonal reaction also termed Cu-free click reaction.  This reaction has excellent selectivity and biocompatibility, such that the complimentary reagents can form covalent bonds with richly functionalized biological systems. The Cu-free click reaction has been a powerful tool in catalyst-free bioconjugation. DBCO reagents posses fast kinetcs and stability in aqueous buffer and they can be used to label azide-modified biomolecules with high specificity and reactivity. 

Physical Properties:
Yellow/pale-yellow solid or viscous liquid;
Soluble in DMSO or DMF;
Storage Conditions:
Store at -20 0C, desiccate. NHS tends to hydrolyze from moisture. Avoid frequent thaw and frozen.

 

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TCO-Tetrazine Ligation Chemistry產(chǎn)品列表：
TCO-PEG4-NHS ester
UV-Tracer TCO-NHS ester
TCO-NHS ester
TCO-PEG3-Maleimide
TCO-Amine HCl salt
TCO-PEG12-DBCO
Tetrazine-PEG5-NHS ester
Tetrazine-PEG4-Maleimide
Tetrazine-PEG4-Alkyne
Tetrazine-DBCO
Tetrazine-PEG4-Azide
Tetrazine – Fluorescent Dye Conjuagtes
Copper-catalyzed Click Chemistry產(chǎn)品列表：
Alkyne-PEG4-NHS ester
Propargyl-NHS ester
Alkyne-PEG4-Acid
Alkyne-PEG4-Amine
Alkyne-PEG4-Maleimide
Propargyl-Maleimide
Fluorescent Alkynes
Biotin-PEG4-Alkyne
Diazo Biotin-Alkyne
Fluorescent Azides
Azido-PEG4-NHS ester
Azidoacetic acid NHS ester
UV-Tracer Azido-NHS ester
Azido-PEG4-Acid
Azido-PEG3-Maleimide
Azido-Propylamine
Azido-PEG3-Amine
Biotin-PEG3-Azide
TAMRA-Azide-Biotin
Diazo Biotin-Azide
Sulfo-link-Biotin-Azide
Copper-free Click Chemistry產(chǎn)品列表：
DBCO-PEG4-NHS ester
DBCO-PEG4-4-Formylbenzoate
DBCO-Sulfo-NHS ester
DBCO-NHS ester
DBCO-Acid

DBCO-PEG4-Acid
DBCO-Amine
DBCO-PEG4-Amine
DBCO-Maleimide
DBCO-PEG4-Maleimide
Fluorescent Probes
DBCO-Sulfo-link-Biotin
DBCO-PEG12-Biotin Conjugate
DBCO-PEG4-Biotin
Diazo Biotin-DBCO
DBCO-S-S-PEG3-Biotin

DBCO-S-S-PEG3-Biotin
DBCO-PEG4-Phosphoramidite
DBCO-PEG4-Hydroxyl
DBCO-PEG4-4-Formylbenzoate
Tetrazine-DBCO
DBCO-PEG4-DBCO
TCO-PEG12-DBCO

 

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