英文名：ICG NHS ester

     ICG-OSu

     Indocyanine Green N-succinimidyl ester

中文名：吲哚菁綠-琥珀酰亞胺酯

     吲哚菁綠-活性酯

分子式: C49H53N3O7S

分子量: 828.03

外 觀：綠色粉末

溶解性：溶于DMSO或DMF

純 度：95%

保 存：-20℃避光

激發(fā)發(fā)射波長:785/821nm

描 述：ICG is a NIR fluorescent substance which obtain license for clinical uses from US ink" style="word-break: break-all; text-size-adjust: none; color: rgb(34, 85, 136);">FDA(/article/11/) (Food and Drug administration), along with Methylene Blue. It is used in Ophthalmologic angiography, liver function tests, solid tumor detection in surgical operation and angiography.

Because ICG effectively absorbs near infrared wavelength that is about 800nm and its absorption ratio for wavelength of visible light range is low, noises caused by Autofluorescence is low.

ICG NHS ester is a product that has the most representative NHS ester reactive group for labeling amine. Because it rapidly and high-specifically reacts to Primary amine (-NH2), it can label Protein containing amine (-NH2), Antibody and Amine-modified Oligonucleotide in a short time period.

近紅外熒光染料Near IRDyes激發(fā)和發(fā)射波長和顏色圖：

 

ICG NHS ester的NHS可以和蛋白、多肽或抗體上面的NH2發(fā)生反應鏈接到一起。

ICG-maleimide的馬來酰亞胺可以和蛋白、多肽、小分子或抗體上的SH巰基反應連接。

ICG-Amine的NH2可以和蛋白、多肽小分子上面的NHS反應連接起來。

ICG和PEG鏈接可在體內長循環(huán)。

供應商：陜西新研博美生物科技有限公司

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