英文名稱(chēng)：Propargyl-PEG1-acid

       Propargyl-PEG1-COOH

       3-Prop-2-ynoxypropanoic acid
分子式：C6H8O3

分子量：128.1
CAS NO: 55683-37-9

MDL number:MFCD10689189

結(jié)構(gòu)式：


純度:95%

保存方法:-20°C避光，避濕

產(chǎn)品簡(jiǎn)介：

Propargyl-PEG1-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG1-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

This is a crosslinker with an alkyne group on one end and a carboxyl group on the other end. The alkyne can be used to attach to an azide using copper-catalyzed click chemistry. The compound contains a single PEG unit to help improve solubility.

其他同系列產(chǎn)品：

propargyl-PEG1-Acid        55683-37-9        

propargyl-PEG3-Acid        1347760-82-0      

Propargyl-PEG4-acid        1415800-32-6

propargyl-PEG5-Acid        1245823-51-1

Propargyl-PEG2-amine        944561-44-8   

Propargyl-PEG3-amine        932741-18-9

Propargyl-PEG4-amine        1013921-36-2

Propargyl-PEG5-amine        1589522-46-2

Propargyl-PEG6-amine        1198080-04-4 

Propargyl-PEG3-azide        932741-18-9     

Propargyl-PEG4-Maleimide     1609651-90-2      

Propargyl-PEG3-NHS ester     1428629-71-3

Propargyl-PEG4-NHS ester     1428629-70-2      

Propargyl-PEG5-NHS ester     1393330-40-9

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