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詳細(xì)介紹
菁染料熒光探針Cyanine7.5 azide,Cy7.5 N3
性狀：綠色粉末/溶液
分子量：767.44
分子式：C48H55ClN6O
溶解度：溶于有機(jī)溶劑（DMSO、DMF、二氯甲烷），水溶性低。
質(zhì)量控制：純度>95%
儲(chǔ)存條件：在-20°C中24個(gè)月
運(yùn)輸：室溫下長(zhǎng)達(dá)3周。避免長(zhǎng)時(shí)間接觸光線。變干。
菁染料熒光探針Cyanine7.5 azide,Cy7.5 N3
產(chǎn)品簡(jiǎn)介：Cyanine7.5 is a NIR dye with long-wave infrared fluorescence. This derivative is azide for Click Chemistry.
Can be used for the construction of various labeled biomolecules containing Cyanine7.5, near infrared fluorescent dye, and an improved analog of Cy7.5®. These conjugates can take advantage of NIR tissue transparency when used for in vivo imaging. This fluorophore is also useful for other fluorescent applications, especially requiring low fluorescent background.
Azide is available as DMSO solution, ready for general Click Chemistry labeling protocol, or in solid form for custom labeling applications.
Structure features rigid bridged polymethyne chain to increase quantum yield by 20%, allowing for brighter signal.
產(chǎn)品一：CY3/CY3.5/CY5/CY5.5.CY7.5
菁染料是近紅外熒光染料中zui常用的一類熒光染料，統(tǒng)的可見光染料相比有顯著的優(yōu)勢(shì)。由于細(xì)胞和組織的自發(fā)熒光在近紅外波段zui小，因此在檢測(cè)復(fù)雜生物系統(tǒng)時(shí)，近紅外染料能提供更高的特異性和靈敏度。同時(shí)，由于光波在近紅外區(qū)段的組織透過(guò)性更好。菁染料的摩爾吸光系數(shù)在熒光染料中是zui高的，Cy7 NHS ester, Cy5.5 amine 和Cy3 azide 的吸收在近紅外區(qū)背景非常低，是熒光強(qiáng)度zui高、zui穩(wěn)定的長(zhǎng)波長(zhǎng)染料。特別適合于活體小動(dòng)物體內(nèi)成像代替放射性元素。
CY花菁染料的優(yōu)點(diǎn)：
1：菁染料的摩爾吸光系數(shù)在熒光染料中是zui高的
2：細(xì)胞和組織的自發(fā)熒光在近紅外波段zui小
3：更高的特異性和靈敏度
4：光波在近紅外區(qū)段的組織透過(guò)性更好
5：染料細(xì)胞毒性小 可用于標(biāo)記抗體 蛋白 細(xì)胞。
因此CY花菁染料是非常適合做小鼠活體成像的熒光染料
CY花菁染料的缺點(diǎn)：
1：菁染料的熒光量子效率相比其他染料較低，一般是0.1-0.2
2：多川結(jié)構(gòu)的菁染料容易發(fā)生聚集
CY花菁染料的價(jià)格特點(diǎn)：
目前市面上的菁染料價(jià)格比較高，主要是因?yàn)檩既玖? 尤其是不對(duì)稱菁染料的合成副反應(yīng)多, 副產(chǎn)物極性相近, 產(chǎn)物的分離提純相當(dāng)困難。菁染料特別是水溶性菁染料分子極性大, 分離提純?cè)郊永щy，因此帶磺酸根的水溶花菁染料比脂溶的貴一些。陜西新研博美生物科技有限公司提供的CY染料 各種活性基團(tuán)的脂溶的一律2050/10MG，以及水溶的各種基團(tuán)的一律2850/10MG
CY系列的產(chǎn)品目錄：
CY3-COOH
Cyanine3-NHS ester
CY3-NH2
Cyanine3-azide
CY3-alkyne
CY3-MAL
Cyanine3-hydrazide
CY3-SH
2050/10mg 3850/25mg 6500/50mg
Sulfo-CY3-COOH
Sulfo-CY3-NHS ester
Sulfo- Cyanine3-NH2
Sulfo-CY3-azide
Sulfo-CY3-alkyne
Sulfo- Cyanine3-MAL
Sulfo-CY3-hydrazide
Sulfo- Cyanine3-SH
2850/10mg 5500/25mg 9500/50mg
Cyanine3.5-COOH
CY3.5-NHS ester
CY3.5-NH2
Cyanine3.5-azide
Cyanine3.5-alkyne
CY3.5-MAL
Cyanine3.5-hydrazide
CY3.5-SH
2050/10mg 3850/25mg 6500/50mg
Sulfo-CY3.5-COOH
Sulfo- Cyanine3.5-NHS ester
Sulfo-CY3.5-NH2
Sulfo-CY3.5-azide
Sulfo- Cyanine3.5-alkyne
Sulfo-CY3.5-MAL
Sulfo- Cyanine3.5-hydrazide
Sulfo- Cyanine3.5-SH
2850/10mg 5500/25mg 9500/50mg
Cyanine5-COOH
CY5-NHS ester
Cyanine5-NH2
CY5-azide
CY5-alkyne
CY5-MAL
CY5-hydrazide
CY5-SH
2050/10mg 3850/25mg 6500/50mg
Sulfo-CY5-COOH
Sulfo- Cyanine5-NHS ester
Sulfo- Cyanine5-NH2
Sulfo- Cyanine5-azide
Sulfo-CY5-alkyne
Sulfo-CY5-MAL
Sulfo-CY5-hydrazide
Sulfo-CY5-SH
2850/10mg 5500/25mg 9500/50mg
CY5.5-COOH
CY5.5-NHS ester
Cyanine5.5-NH2
Cyanine5.5-azide
CY5.5-alkyne
CY5.5-MAL
CY5.5-hydrazide
CY5.5-SH
2050/10mg 3850/25mg 6500/50mg
Sulfo-Cyanine5.5-COOH
Sulfo-Cyanine5.5-NHS ester
Sulfo-CY5.5-NH2
Sulfo- Cyanine5.5-azide
Sulfo-CY5.5-alkyne
Sulfo-CY5.5-MAL
Sulfo-CY5.5-hydrazide
Sulfo-CY5.5-SH
2850/10mg 5500/25mg 9500/50mg
CY7-COOH
CY7-NHS ester
Cyanine7-NH2
CY7-azide
CY7-alkyne
Cyanine7-MAL
CY7-hydrazide
CY7-SH
2050/10mg 3850/25mg 6500/50mg
Sulfo-CY7-COOH
Sulfo- Cyanine7-NHS ester
Sulfo- Cyanine7-NH2
Sulfo- Cyanine7-azide
Sulfo- Cyanine7-alkyne
Sulfo-CY7-MAL
Sulfo-CY7-hydrazide
Sulfo-CY7-SH
2850/10mg 5500/25mg 9500/50mg
CY7.5-COOH
CY7.5-NHS ester
Cyanine7.5-NH2
CY7.5-azide
CY7.5-alkyne
Cyanine7.5-MAL
CY7.5-hydrazide
Cyanine7.5-SH
2050/10mg 3850/25mg 6500/50mg
Sulfo-CY7.5-COOH
Sulfo-CY7.5-NHS ester
Sulfo-CY7.5-NH2
Sulfo- Cyanine7.5-azide
Sulfo- Cyanine7.5-alkyne
Sulfo-CY7.5-MAL
Sulfo-CY7.5-hydrazide
Sulfo-CY7.5-SH
2850/10mg 5500/25mg 9500/50mg
Coumarin香豆素系列產(chǎn)品二：
香豆素化合物作為熒光材料具有很多優(yōu)點(diǎn)，如光物理和光化學(xué)性質(zhì)可調(diào)、熒光量子產(chǎn)率高、Stokes位移大以及光穩(wěn)定性好等，因此基于香豆素染料的熒光探針是一大研究熱點(diǎn)
陜西新研博美生物科技有限公司是國(guó)內(nèi)的熒光染料供應(yīng)商，我可以提供包括有香豆素?zé)晒庋苌锂a(chǎn)品，波長(zhǎng)是是400-550nm，我們可以再香豆素末端修飾NHS活化脂、疊氮N3、MAL馬來(lái)酰亞胺，氨基NH2等等活性基團(tuán)，除此之外我們還可以提供BODIPY熒光活性染料，CY系列活性熒光染料等等產(chǎn)品。
產(chǎn)品優(yōu)點(diǎn)：
1：Stokes位移大
2：相對(duì)較高的量子產(chǎn)品率0.2-0.4
3：可以提供雙光子香豆素產(chǎn)品
產(chǎn)品缺點(diǎn)：
1：香豆素的波長(zhǎng)選擇范圍窄只有400-600之間選
Coumarin香豆素的產(chǎn)品列表：
Benzo-Coumarin-380 Ex/Em:380nm-540nm
Benzo-Coumarin-400 Ex/Em:400nm-570nm
Benzo-Coumarin-420 Ex/Em:420nm-570nm
Benzo-Coumarin-400 carboxylic acid Ex/Em:400nm-550nm
Benzo-Coumarin-465 carboxylic acid Ex/Em:465nm-610nm
PEG- BComarin465 carboxylic acid Ex/Em:465nm-610nm
Benzo-Coumarin-400 amine Ex/Em:400nm-550nm
Sulfo-BComarin400 amine Ex/Em:400nm-550nm
BComarin465 amine Ex/Em:465nm-610nm
PEG-BComarin465 amine Ex/Em:465nm-610nm
BComarin400 azide Ex/Em:400nm-550nm
Sulfo-BComarin400 azide Ex/Em:400nm-550nm
BComarin465 azide Ex/Em:465nm-610nm
PEG-BComarin465 azide Ex/Em:465nm-610nm
Sulfo-BComarin400 NHS ester Ex/Em:400nm-550nm
BComarin465 NHS ester Ex/Em:465nm-610nm
PEG-BComarin465 NHS ester Ex/Em:465nm-610nm
BComarin400 alkyne Ex/Em:400nm-550nm
Sulfo-BComarin400 alkyne Ex/Em:400nm-550nm
BComarin465 alkyne Ex/Em:465nm-610nm
PEG-BComarin465 alkyne Ex/Em:465nm-610nm
BComarin400 maleimide Ex/Em:400nm-550nm
Sulfo-BComarin400 maleimide Ex/Em:400nm-550nm
BComarin465 maleimide Ex/Em:465nm-610nm
PEG-BComarin465 maleimide Ex/Em:465nm-610nm
其他部分產(chǎn)品列表：
Coumarin 343 X NHS ester Ex/Em:430nm-470nm
Coumarin NHS ester Ex/Em:400nm-450nm
Coumarin NHS ester Ex/Em:450nm-490nm
Coumarin NHS ester Ex/Em:470nm-510nm
Coumarin 343 X azide Ex/Em:430nm-470nm
Coumarin 343 azide
Coumarin azide Ex/Em:490nm-530nm
Coumarin azide Ex/Em:480nm-520nm
Coumarin 343 X alkyne Ex/Em:430nm-470nm
Coumarin alkyne Ex/Em:410nm-460nm
Coumarin 343 X maleimide Ex/Em:430nm-470nm
Coumarin maleimide Ex/Em:440nm-480nm
Coumarin 343 X carboxylic acid Ex/Em:430nm-470nm
Coumarin carboxylic acid Ex/Em:440nm-480nm
Coumarin 343 X amine Ex/Em:430nm-470nm
Coumarin amine Ex/Em:440nm-480nm
Coumarin 343 X Thiol Ex/Em:430nm-470nm
Coumarin Thiol Ex/Em:440nm-480nm
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