55683-37-9 Propargyl-PEG1-COOH供應(yīng)商

55683-37-9 Propargyl-PEG1-COOH供應(yīng)商

英文名稱(chēng)：Propargyl-PEG1-acid

       Propargyl-PEG1-COOH

       3-Prop-2-ynoxypropanoic acid
分子式：C6H8O3

分子量：128.1
CAS NO: 55683-37-9

MDL number:MFCD10689189

結(jié)構(gòu)式：


純度:95%

保存方法:-20°C避光，避濕

產(chǎn)品簡(jiǎn)介：

Propargyl-PEG1-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG1-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

This is a crosslinker with an alkyne group on one end and a carboxyl group on the other end. The alkyne can be used to attach to an azide using copper-catalyzed click chemistry. The compound contains a single PEG unit to help improve solubility.

55683-37-9 Propargyl-PEG1-COOH供應(yīng)商