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38次產(chǎn)品名稱:Rabbit Anti-UTF1 antibody
別名:hUTF 1; hUTF1; Undifferentiated embryonic cell transcription factor 1; UTF 1; UTF1_HUMAN.
反應(yīng):Human (predicted: Mouse,Rat,Cow)
免疫原:KLH conjugated synthetic peptide derived from Human UTF1
單克隆抗體
產(chǎn)品名稱:Anti-UTF1 antibody
Mouse Anti-UTF1
別名:hUTF 1; hUTF1; Undifferentiated embryonic cell transcription factor 1; UTF 1; UTF1_HUMAN.
來源:Mouse
克隆類型:Monoclonal
濃度:1mg/ml
亞型:IgG
應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應(yīng): Human
理論分子量:36kDa
免疫原:KLH conjugated synthetic peptide derived from Human UTF1
保存:-20℃
保質(zhì)期:1年
UTF1 is a 341 amino acid protein that localizes to the nucleus and is subject to post-translational phosphorylation. Associating with the TFIID complex via an interaction with the TATA box binding protein (TFIID), UTF1 binds to the N-terminal region of ATF-2 and, via this binding, acts as a transcriptional coactivator of ATF-2, thereby enhancing transcriptional activity. Human UTF1 shares 64% homology with its mouse counterpart, suggesting a similar role between species. The gene encoding UTF1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
hUTF 1; hUTF1; Undifferentiated embryonic cell transcription factor 1; UTF 1; UTF1_HUMAN.
表達(dá)系統(tǒng):Escherichia coli
應(yīng)用:SDS-PAGE,Western blot,ELISA
Biological activity,immunology research
UTF1 is a 341 amino acid protein that localizes to the nucleus and is subject to post-translational phosphorylation. Associating with the TFIID complex via an interaction with the TATA box binding protein (TFIID), UTF1 binds to the N-terminal region of ATF-2 and, via this binding, acts as a transcriptional coactivator of ATF-2, thereby enhancing transcriptional activity. Human UTF1 shares 64% homology with its mouse counterpart, suggesting a similar role between species. The gene encoding UTF1 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
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