MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報(bào)，我們不為任何個(gè)人用途提供產(chǎn)品和服務(wù)。

Eugenol

CAS No. : 97-53-0

產(chǎn)品活性：Eugenol is an essential oil found in cloves with antibacterial, anthelmintic and antioxidant activity. Eugenol is shown to inhibit lipid peroxidation.

研究領(lǐng)域：Anti-infection  |  Metabolic Enzyme/Protease  |  Immunology/Inflammation  |  NF-κB  |  Apoptosis

作用靶點(diǎn)：Bacterial  |  Parasite  |  Reactive Oxygen Species  |  Apoptosis  |  Ferroptosis

結(jié)構(gòu)分類：苯丙素類  |  簡單苯丙素  |  酚類  |  單酚類

來源：植物  |  桃金娘科  |  丁香

In Vitro: The essential oil of O. gratissimum, as well as eugenol, are efficient in inhibiting eclodibility of H. contortus eggs, showing possible utilizations in the treatment of gastrointestinal helmintosis of small ruminants. At 0.50% concentration, the essential oil and eugenol show a maximum eclodibility inhibition. Eugenol inhibits superoxide anion generation in xanthine-xanthine oxidase system to an extent of 50% at concentrations of 250 μM. Eugenol also inhibits the generation of hydroxyl radicals to an extent of 70%. The OH-radical formation measured by the hydroxylation of salicylate to 2, 3-dihydroxy benzoate is inhibited to an extent of 46% by eugenol at 250 μM. Eugenol protects against RS-induced development of IBS-like gastrointestinal dysfunction through modulation of HPA-axis and brain monoaminergic pathways apart from its antioxidant effect. Eugenol (50?mg/kg) reduces 80% of RS-induced increase in fecal pellets similar to that of ondansetron. Eugenol attenuates 80% of stress-induced increase in plasma corticosterone and modulates the serotonergic system in the PFC and amygdala. Eugenol attenuates stress-induced changes in norepinephrine and potentiates the antioxidant defense system in all brain regions.

In Vivo: Eugenol (33 mg/kg) administered orally for 2 days causes significant suppression of knee joint edema, which continues to be significantly reduced at the end of the treatment. After 2 days, eugenol-treated mycobacterial arthritic rats show a marked reduction in paw swelling.

相關(guān)產(chǎn)品：Natural Product Library Plus  |  Drug Repurposing Compound Library Plus  |  FDA-Approved Drug Library Plus  |  FDA-Approved Drug Library Mini  |  Bioactive Compound Library Plus  |  Anti-Infection Compound Library  |  Apoptosis Compound Library  |  Immunology/Inflammation Compound Library  |  Metabolism/Protease Compound Library  |  NF-κB Signaling Compound Library  |  Stem Cell Signaling Compound Library  |  Natural Product Library  |  FDA-Approved Drug Library  |  Anti-Cancer Compound Library  |  Fragment Library  |  Anti-Aging Compound Library  |  Drug Repurposing Compound Library  |  Antioxidant Compound Library  |  Oxygen Sensing Compound Library  |  Antibacterial Compound Library  |  Ferroptosis Compound Library  |  NMPA-Approved Drug Library  |  Medicine Food Homology Compound Library  |  Phenols Library  |  Pyroptosis Compound Library  |  Orally Active Compound Library  |  Traditional Chinese Medicine Active Compound Library  |  FDA Approved & Pharmacopeial Drug Library  |  Drug-Induced Liver Injury (DILI) Compound Library  |  Antiparasitic Compound library  |  Mitochondria-Targeted Compound Library  |  Food Additive Library   |  Food-Sourced Compound Library   |  Children’s Drug Library  |  Anti-Cancer Natural Product Library  |  Anti-inflammatory Traditional Chinese Medicine Active Compound Library  |  Plant-Sourced Natural Product Library  |  FDA-Approved Anticancer Drug Library  |  Human Metabolite Library  |  Non-steroidal Anti-Inflammatory Compound Library  |  Off-patent Drug Library  |  SY-5609  |  Antifungal agent 26  |  D-α-Hydroxyglutaric acid disodium  |  BRD4 Inhibitor-18  |  8α-Tigloyloxyhirsutinolide 13-O-acetate  |  (1R,2S,7R)-Sitafloxacin-d₄ (hydrochloride)  |  Quinidine-d₃  |  Nebacumab  |  Angulatin G  |  Acridine Orange base  |  N-Desethyl amodiaquine-d₅  |  Gepotidacin  |  Amycolatopsin A  |  Palitantin  |  Antibiotic A-33853  |  Estradiol hemihydrate  |  AAPK-25  |  Sulbactam-d₂ (sodium)  |  Dutasteride-¹³C₆  |  Oleic acid-¹³C  |  Antimicrobial agent-5  |  Proguanil-d₆  |  NBTIs-IN-4  |  Proanthocyanidin  |  Azlocillin sodium salt  |  Abacavir sulfate  |  Antitubercular agent-13  |  Meloxicam-d₃-1  |  7-Hydroxy-4-methyl-2(1H)-quinolone

熱門產(chǎn)品線：重組蛋白  |  化合物庫  |  天然產(chǎn)物  |  熒光染料  |  PROTAC  |  同位素標(biāo)記物  |  寡核苷酸  |  抗體  |  點(diǎn)擊化學(xué)

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides  |  Antibodies  |  Click Chemistry

品牌介紹:
•   MCE (MedChemExpress) 擁有200 多種*僅有化合物庫，我們致力于為*科研客戶提供前沿的高品質(zhì)小分子活性化合物；
•   50,000 多種高選擇性抑制劑、激動(dòng)劑涉及各熱門信號通路及疾病領(lǐng)；
•   產(chǎn)品種類涵蓋各種重組蛋白，多肽，常用試劑盒 ，更有 PROTAC、ADC 等特色產(chǎn)品，廣泛應(yīng)用于新藥研發(fā)、生命科學(xué)等科研項(xiàng)目；
•   提供虛擬篩選，離子通道篩選，代謝組學(xué)分析檢測分析，藥物篩選等專業(yè)技術(shù)服務(wù)；
•   設(shè)有專業(yè)的實(shí)驗(yàn)中心和嚴(yán)格的質(zhì)控、驗(yàn)證體系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各項(xiàng)質(zhì)檢報(bào)告，確保產(chǎn)品的高純度、高品質(zhì)；
•   產(chǎn)品的生物活性多經(jīng)各國客戶實(shí)驗(yàn)驗(yàn)證；
•   Nature, Cell, Science 等多種頂級期刊及制藥 Patent 收錄了MCE客戶的科研成果；
•   專業(yè)團(tuán)隊(duì)跟蹤最新的制藥及生命科學(xué)研究進(jìn)展，為您提供*新的活性化合物；
•   與世界各大制藥公司及著名科研機(jī)構(gòu)建立了長期的合作。