目錄:MedChemExpress LLC>>生化試劑>> Acipimox sodium | MCE
CAS | 76958-97-9 | 分子量 | 176.11 |
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分子式 | C?H?N?NaO? | 供貨周期 | 現(xiàn)貨 |
貨號 | HY-B0283A | 應用領域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
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CAS No. : 76958-97-9
產(chǎn)品活性:Acipimox (K-9321) sodium, a nicotinic acid analogue, is an antilipolytic compound. Acipimox sodium stimulates leptin releas, inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity.
研究領域:Others
作用靶點:Others
In Vitro: Acipimox sodium (0-100 µM; 0-4 hours) enhances leptin release from adipocytes isolated from Sprague-Dawley rats in a time- and dose- dependent manner.
Acipimox sodium (10 mM) stimulats leptin release in adipocytes from Streptozotocin (STZ)-treated and Zucker diabetic fat (ZDF) rats.
In Vivo: Acipimox sodium (50 mg/kg; i.p.) significantly lowers circulating free fatty acid (FFA) and glucose in high-fat fed mice.
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