目錄:MedChemExpress LLC>>生化試劑>> L-Leucyl-L-Leucine methyl ester hydrobromide | MCE
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參考價(jià) | ¥ 800 |
更新時(shí)間:2023-06-19 09:21:14瀏覽次數(shù):207評(píng)價(jià)
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CAS | 16689-14-8 | 純度 | 99.81% |
---|---|---|---|
分子量 | 339.27 | 分子式 | C??H??BrN?O? |
供貨周期 | 現(xiàn)貨 | 規(guī)格 | 10 mg |
貨號(hào) | HY-129905A | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
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CAS No. : 16689-14-8
產(chǎn)品活性:L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrobromide also can induce endolysosomal pathway stress.
研究領(lǐng)域:Metabolic Enzyme/Protease
作用靶點(diǎn):Endogenous Metabolite
In Vitro: L-Leucyl-L-Leucine methyl ester (1 mM; 0.5-2 h) enhances LRRK2-mediated Rab10 and Rab12 phosphorylation in MEFs and A549 cells.
L-Leucyl-L-Leucine methyl ester (10-250 μM; 15 min) is converted to a CCI3COOH-insoluble product by CD4- lymphocytes.
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