目錄:MedChemExpress LLC>>生化試劑>> Niacin hydrochloride | MCE
CAS | 636-79-3 | 分子量 | 159.57 |
---|---|---|---|
分子式 | C?H?ClNO? | 供貨周期 | 現(xiàn)貨 |
貨號 | HY-B0143A | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報,我們不為任何個人用途提供產(chǎn)品和服務(wù)。
CAS No. : 636-79-3
產(chǎn)品活性:Niacin (Vitamin B3; Nicotinic acid) hydrochloride is an orally active B3 vitamin that is an essential nutrient for humans. Niacin hydrochloride plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin hydrochloride is also used in the study of cardiovascular diseases.
研究領(lǐng)域:Metabolic Enzyme/Protease | Apoptosis
作用靶點:Endogenous Metabolite | Apoptosis
In Vitro: Niacin hydrochloride (0-900 μM, 42 hours) significantly increases GSH levels and decreases ROS levels, and affects the expression of genes related to apoptosis and lipid metabolism.
Niacin hydrochloride (0-40 μM, 24 hours) can inhibit cancer invasive activity at low dose but with no influence on proliferation.
In Vivo: Niacin hydrochloride (subcutaneous injection, 3-300 mg/kg, once) can induce vasodilation in a dose-dependent manner within minutes in male C57BL/6 mice.
相關(guān)產(chǎn)品:D-Valine-d8 | SY-5609 | D-α-Hydroxyglutaric acid disodium | BRD4 Inhibitor-18 | Nicotinamide N-oxide | 8α-Tigloyloxyhirsutinolide 13-O-acetate | Deoxycholic acid-d5 | Doxorubicin-13C,d3 (TFA) | Palitantin | Estradiol hemihydrate | AAPK-25 | Dutasteride-13C6 | Adrenaline sulfate | Oleic acid-13C | Dextranase | H2S Donor 5a | Abacavir sulfate | Methylmalonic acid | Meloxicam-d3-1 | Glycine, N-(aminoiminomethyl)-N-methyl-13C | Dihydroxyacetone phosphate | Thailanstatin D | SB-218078 | Toyocamycin | Sorafenib-d4 | Sphingomyelin | (-)-Jasmonoyl-L-isoleucine | Busulfan | PTC-028 | Dinaciclib
熱門產(chǎn)品線:重組蛋白 | 化合物庫 | 天然產(chǎn)物 | 熒光染料 | PROTAC | 同位素標記物 | 寡核苷酸 | 抗體 | 點擊化學(xué)
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides | Antibodies | Click Chemistry
品牌介紹:
• MCE (MedChemExpress) 擁有200 多種全球僅有化合物庫,我們致力于為全球科研客戶提供前沿的高品質(zhì)小分子活性化合物;
• 50,000 多種高選擇性抑制劑、激動劑涉及各熱門信號通路及疾病領(lǐng);
• 產(chǎn)品種類涵蓋各種重組蛋白,多肽,常用試劑盒 ,更有 PROTAC、ADC 等特色產(chǎn)品,廣泛應(yīng)用于新藥研發(fā)、生命科學(xué)等科研項目;
• 提供虛擬篩選,離子通道篩選,代謝組學(xué)分析檢測分析,藥物篩選等專業(yè)技術(shù)服務(wù);
• 設(shè)有專業(yè)的實驗中心和嚴格的質(zhì)控、驗證體系;
• 提供 LC/MS、NMR、HPLC、手性分析、元素分析等各項質(zhì)檢報告,確保產(chǎn)品的高純度、高品質(zhì);
• 產(chǎn)品的生物活性多經(jīng)各國客戶實驗驗證;
• Nature, Cell, Science 等多種頂級期刊及制藥 Patent 收錄了MCE客戶的科研成果;
• 專業(yè)團隊跟蹤最新的制藥及生命科學(xué)研究進展,為您提供全球新的活性化合物;
• 與世界各大制藥公司及著名科研機構(gòu)建立了長期的合作。