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Forskolin (GMP)

CAS No. : 66575-29-9

產(chǎn)品活性：Forskolin (Coleonol) (GMP) is Forskolin (HY-15371) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Forskolin is a potent adenylate cyclase activator and inducer of intracellular cAMP formation.

研究領(lǐng)域：GPCR/G Protein  |  Metabolic Enzyme/Protease  |  Autophagy

作用靶點：Adenylate Cyclase  |  FXR  |  Autophagy

In Vitro: Forskolin (GMP) (10 μM, 21 days) transdifferentiates mouse fibroblasts to neurons, determined by increased number of TAUEGFP-/TUJ1-positive neuronal cells induced by Ascl1.
Forskolin (GMP) (25 μM, in hHPC maturation medium) induces hCiPS-cell-derived hHPCs to differentiate into mature hepatocytes (the detailed method refers to the reference).
Forskolin (GMP) (10?μM, during 5-15 days) induces human fibroblasts (HFF) reprogramming into functional cardiomyocytes.
Forskolin (GMP) (in MEFs expressing MyoD) enhances the marked increase in the number of proliferative cells together with RepSox (GMP) (HY-13012G).
Forskolin (GMP) (10 μM, during 2-4 days) can be used to generate islets (hCiPSC-islets) from human chemically induced pluripotent stem cells (hCiPSC).

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