目錄:MedChemExpress LLC>>信號通路>> GW 441756 | MedChemExpress
| CAS | 504433-23-2 | 純度 | 99.95% |
|---|---|---|---|
| 分子量 | 275.3 | 分子式 | C??H??N?O |
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 10 mM * 1 mL |
| 貨號 | HY-18314 | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報，我們不為任何個人用途提供產(chǎn)品和服務(wù)。
CAS No. : 504433-23-2
MCE 國際站：GW 441756
產(chǎn)品活性：GW 441756 是一種高效特異性神經(jīng)生長因子 (NGF) 受體酪氨酸激酶 a (TrkA) 抑制劑 (IC50=2 nM)，可消除 BmK NSPK-induced 神經(jīng)突生長。
研究領(lǐng)域：Neuronal Signaling | Protein Tyrosine Kinase/RTK | Apoptosis
作用靶點：Trk Receptor | Apoptosis
In Vitro: GW-441756 (1 μM; 48 hours; spinal cord neurons cells) abolishs BmK NSPK-induced neurite outgrowth.
?GW-441756 (1 μM; 4 hours; PC12 cells) inhibits nerve growth factor induced neurite outgrowth.
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