目錄:MedChemExpress LLC>>信號(hào)通路>> Delamanid | MedChemExpress (MCE)
| 參考價(jià) | ￥ 590 |
| 參考價(jià) | ￥ 590 |
更新時(shí)間：2023-11-30 11:28:13瀏覽次數(shù)：179評(píng)價(jià)
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| CAS | 681492-22-8 | 純度 | 99.96% |
|---|---|---|---|
| 分子量 | 534.48 | 分子式 | C??H??F?N?O? |
| 供貨周期 | 現(xiàn)貨 | 規(guī)格 | 10 mM * 1 mL |
| 貨號(hào) | HY-10846 | 應(yīng)用領(lǐng)域 | 醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥 |
MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報(bào)，我們不為任何個(gè)人用途提供產(chǎn)品和服務(wù)。
CAS No. : 681492-22-8
MCE 國際站：Delamanid
產(chǎn)品活性：Delamanid是一個(gè)用于耐多藥結(jié)核病的化合物，也是新的分枝桿菌細(xì)胞壁合成抑制劑。
研究領(lǐng)域：Anti-infection
作用靶點(diǎn)：Bacterial | Antibiotic
In Vitro: Delamanid inhibits the synthesisi of mucolic acids, cruciala component of the cell wall of the Mycobacterium tuberculosis complex. Delamanid shows more potent antibacterial activity against drug-susceptible and drug-resistant strains of M. tuberculosis. Delamanid do not affect rifampin, pyrazinamide, and isoniazid exposure; the ethambutol AUCτ and Cmax values are about 25% higher with delamanid coadministration.
In Vivo: Delamanid (orally administration; 30 mg/kg; 5 days) results in sterile cures in a mouse model of VL.
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