MDM2 TR-FRET Assay Kit 返回列表頁

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產(chǎn)品型號(hào)79773

品牌BPS Bioscience

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Ubiquitination

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●Purchase●DescriptionHumanMousedoubleminute2homolog (MDM2)isanE3ubiquitin-proteinligasethatfunctionsasanegativeregulatorofT-cellactivation

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Description

Human Mouse double minute 2 homolog (MDM2) is an E3 ubiquitin-protein ligase that functions as a negative regulator of T-cell activation. It is a potential drug target in cancer immunotherapy. It utilizes biotin-labeled ubiquitin and a terbium-labeled anti-GST antibody to complete the TR-FRET pairing. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications.

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Synonyms

Mdm2,mouse double minute 2, human homolog, Hdm2

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