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目錄:杭州斯達(dá)特生物科技有限公司>>蛋白>>其他.>> S0A0122Mouse DLL4 Protein, His tag

Mouse DLL4 Protein, His tag
  • Mouse DLL4 Protein, His tag
參考價(jià) 1100
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參考價(jià) 1100
具體成交價(jià)以合同協(xié)議為準(zhǔn)
  • 品牌 Starter/斯達(dá)特
  • 型號(hào) S0A0122
  • 廠商性質(zhì) 生產(chǎn)商
  • 所在地 南京市
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更新時(shí)間:2025-07-15 17:48:42瀏覽次數(shù):39評(píng)價(jià)

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Mouse DLL4 Protein, His tag

Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Notch signaling is an evolutionarily conserved pathway that controls cell fate and is required in multiple developmental processes including vascular development, hematopoiesis, somatogenesis, myogenesis, and neurogenesis. Notch signaling is dysregulated in many cancers, and faulty notch signaling is implicated in many diseases, including T-cell acute lymphoblastic leukemia (T-ALL), cerebral autosomal-dominant arteriopathy with sub-cortical infarcts and leukoencephalopathy (CADASIL), multiple sclerosis, Tetralogy of Fallot, and Alagille syndrome. Inhibition of notch signaling inhibits the proliferation of T-cell acute lymphoblastic leukemia in both cultured cells and a mouse model.

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