WIF1抗原，Wnt信號(hào)抑制因子1抗原

Recombinant human WIF1   

WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.  

濃度：1mg/ ml

來源：Recombinant Human

純度：≥95% SDS-PAGE

表達(dá)系統(tǒng)：HEK 293 cells

標(biāo)簽：His tag C-Terminus   

蛋白長度：Full length protein

內(nèi)毒素水平：<1.000 Eu/µg

純化方法：HPLC

應(yīng)用：SDS-PAGE，Western blot，ELISA

Biological activity,immunology research

保存：-20℃

保質(zhì)期：1年

The Wnt genes are a group of conserved, Cysteine-rich, secreted glycoproteins that are required for numerous developmental processes including embryogenesis, asymmetric cell division and central nervous system (CNS) patterning. Wnt association with the transmembrane spanning receptor frizzled activates dishevelled, which downregulates glycogen synthase kinase (GSK) through serine phosphorylation. Reduced levels of active GSK causes accumulation of b-catenin and subsequent regulation of developmentally significant Wnt target genes. Wnt antagonists such as dickkopf (Dkk), frizzled-related protein (sFRP) and Wnt inhibitory factor-1 (WIF-1), are necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes. WIF-1 is a 379-amino acid secreted protein that contains an N-terminal signal sequence, a 150-amino acid WIF domain, five epidermal growth factor-like repeats and a 45-amino acid C-terminal hydrophilic domain.

產(chǎn)品名稱：Rabbit Anti-WIF1 antibody

Rabbit Anti-WIF1 

別名：WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.              

來源：Rabbit

克隆類型：Polyclonal

濃度：1mg/ml

亞型：IgG

反應(yīng)：(predicted: Human,Mouse,Rat,Pig,Cow,Chicken,Dog,Horse)

應(yīng)用： WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

理論分子量：39kDa

免疫原：KLH conjugated synthetic peptide derived from human WIF1

保存：-20℃
保質(zhì)期：1年

產(chǎn)品名稱：Anti-WIF1 antibody

Mouse Anti-WIF1

別名：WIF-1; wif1; WIF1_HUMAN; Wnt Inhibitory Factor 1.                 

來源：Mouse

克隆類型：Monoclonal

濃度：1mg/ml

亞型：IgG

反應(yīng)：Human

應(yīng)用：WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應(yīng):  Human

理論分子量：39kDa

免疫原：KLH conjugated synthetic peptide derived from human WIF1

保存：-20℃
保質(zhì)期：1年

The Wnt genes are a group of conserved, Cysteine-rich, secreted glycoproteins that are required for numerous developmental processes including embryogenesis, asymmetric cell division and central nervous system (CNS) patterning. Wnt association with the transmembrane spanning receptor frizzled activates dishevelled, which downregulates glycogen synthase kinase (GSK) through serine phosphorylation. Reduced levels of active GSK causes accumulation of b-catenin and subsequent regulation of developmentally significant Wnt target genes. Wnt antagonists such as dickkopf (Dkk), frizzled-related protein (sFRP) and Wnt inhibitory factor-1 (WIF-1), are necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes. WIF-1 is a 379-amino acid secreted protein that contains an N-terminal signal sequence, a 150-amino acid WIF domain, five epidermal growth factor-like repeats and a 45-amino acid C-terminal hydrophilic domain.