資料簡介
Recombinant human Wnt1
wingless-type MMTV integration site family, member 1; INT 1; INT1; Murine mammary tumor virus integration site 1 ; Oncogene INT1; Proto oncogene protein Wnt 1; Wnt 1; Wnt1 proto oncogene protein precursor; WNT1_HUMAN.
濃度:1mg/ ml
來源:Recombinant Human
純度:≥95% SDS-PAGE
表達系統(tǒng):Escherichia coli
標(biāo)簽:His tag
蛋白長度:Full length protein
內(nèi)毒素水平:<1.000 Eu/µg
純化方法:HPLC
應(yīng)用:SDS-PAGE,Western blot,ELISA
Biological activity,immunology research
保存:-20℃
保質(zhì)期:1年
TThe WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.
產(chǎn)品名稱:Rabbit Anti-Wnt1 antibody
Rabbit Anti-Wnt1
別名:wingless-type MMTV integration site family, member 1; INT 1; INT1; Murine mammary tumor virus integration site 1 ; Oncogene INT1; Proto oncogene protein Wnt 1; Wnt 1; Wnt1 proto oncogene protein precursor; WNT1_HUMAN.
來源:Rabbit
克隆類型:Polyclonal
濃度:1mg/ml
亞型:IgG
反應(yīng):Human,Mouse,Rat (predicted: Cow,Chicken,Horse)
應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
理論分子量:39kDa
免疫原:KLH conjugated synthetic peptide derived from human Wnt1
保存:-20℃
保質(zhì)期:1年
產(chǎn)品名稱:Anti-Wnt1 antibody
Mouse Anti-Wnt1
別名:wingless-type MMTV integration site family, member 1; INT 1; INT1; Murine mammary tumor virus integration site 1 ; Oncogene INT1; Proto oncogene protein Wnt 1; Wnt 1; Wnt1 proto oncogene protein precursor; WNT1_HUMAN.
來源:Mouse
克隆類型:Monoclonal
濃度:1mg/ml
亞型:IgG
反應(yīng):Human
應(yīng)用:WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應(yīng): Human
理論分子量:39kDa
免疫原:KLH conjugated synthetic peptide derived from human Wnt1
保存:-20℃
保質(zhì)期:1年
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.
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