目錄:北京索萊寶科技有限公司>>細(xì)胞相關(guān)產(chǎn)品>>細(xì)胞因子>> P00025Recombinant Human IL-15細(xì)胞因子
供貨周期 | 現(xiàn)貨 |
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Recombinant Human IL-15細(xì)胞因子
Known as | Interleukin-15; IL-15; IL15 |
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Derived from | E.coli |
Purity | Measured by the dose dependent stimulation of mouse CTLL-2 cell proliferation.ED50 is less than 0.5 ng/ml. Specific Activity of 2.0 x 10^6 IU/mg.Greater than 95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0. |
Shipping | The product is shipped at ambient temperature.Upon receipt, store it immediay at the temperature listed below. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 9 months |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in 7X PBS.Please aliquot the reconstituted solution to minimize freeze-t cycles. |
Endotoxin | Less than 0.1 ng/ug (1 IEU/ug). |
Amino Acid Sequence | NWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKE CEELEEKNIKEFLQSFVHIVQMFINTS |
Background | Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15. |
Recombinant Human Interleukin-15 is produced by our E.coli expression system and the target gene encoding Asn49-Ser162 is expressed.
Recombinant Human IL-15細(xì)胞因子訂購說明:
1、絕大部分產(chǎn)品備有現(xiàn)貨,一般情況下都能訂貨當(dāng)日發(fā)貨。
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常溫產(chǎn)品:常溫產(chǎn)品運(yùn)輸過程中無需加冰或者特殊包裝。產(chǎn)品由公司庫房人員快速配貨,準(zhǔn)確快速高效的快遞保證產(chǎn)品快速送達(dá)您的手中。
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