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IR800-IRDye® 800CW Maleimide
IR800-IRDye® 800CW Maleimide
IR800-IRDye® 800CW Maleimide
西安瑞禧生物科技有限公司可以提供近紅外熒光染料
RDye 800CW is ideal for protein and antibody labeling, or nucleic acid applications with high labeling density. IRDye 800CW is available in the following forms: NHS ester, maleimide,carboxylate, DBCO, azide, alkyne, secondary antibody conjugates, and in labeling kits.
- Optimal performance in Western blotting and immunocytochemical assays
- Superior performance for in vivo imaging
- High water solubility and salt tolerance
- Low non-specific binding to cellular components
- High signal-to-noise ratio
IRDye 800CW and Clinical Translation
LI-COR Clinical Translation seeks to facilitate the use of IRDye 800CW imaging agents in clinical studies for detection of disease and its progression, and for monitoring of treatment and drug efficacy.
IRDye 800CW manufactured under cGMP is intended only for investigational use in clinical trials.
- Used by leading molecular imaging laboratories that develop translatable targeting agents
- Easily conjugated to biomolecules (unlike ICG, which cannot be attached to biomolecules in its clinically approved form)
IRDye 800CW Maleimide provides the functionality for labeling molecules that contain free sulfhydryl (-SH) groups with IRDye 800CW. The reactive group of the IRDye 800CW Maleimide allows conjugation reactions to be performed very efficiently at physiological pH.
IRDye 800CW Maleimide will label molecules with free sulfhydryl (-SH) groups, such as cysteine residues in proteins. Conjugation can be performed at physiological pH.
To discuss commercial development rights using IRDye infrared dyes, please contact Business Development.
[ABOVE] Maleimide reacting with a Thiol group
| Solvent | Ext. Coeff. (M-1cm-1) | Abs Max (nm) | Em Max (nm) |
|---|---|---|---|
| Methanol | 300,000 | 778 | 794 |
| Water | 240,000 | 774 | 789 |
| 1X PBS | 240,000 | 774 | 789 |
| PBS: Methanol | 270,000 | 777 | 791 |
