聯(lián)系電話
- 聯(lián)系人:
- 曹女士
- 電話:
- 400-6111-883
- 手機:
- 售后:
- 4006-111-883
- 傳真:
- 86-21-34615995
- 地址:
- 上海市浦東新區(qū)天雄路166弄1號3樓
- 網(wǎng)址:
- www.yeasen.com
掃一掃訪問手機商鋪
人類疾病的發(fā)展十分復雜,以人本身作為實驗對象來深入探討疾病發(fā)生機制,推動醫(yī)藥學的發(fā)展來之緩慢。借助動物模型的間接研究,可避免在人體上進行實驗所帶來的風險和倫理問題,可以有意識地改變那些在自然條件下不可能或不易排除的因素,以便更準確地觀察模型的實驗結(jié)果并與人類疾病進行比較研究,有助于科研者更方便有效地認識人類疾病的發(fā)生發(fā)展規(guī)律,研究防治措施。
翌圣生物提供多種類型的造模產(chǎn)品,包括結(jié)腸炎、胰腺炎、糖尿病和高血壓等,詳細信息如下表。
不同模型產(chǎn)品選擇指南
<點擊查看詳情>
高品質(zhì)DSS葡聚糖硫酸鈉鹽選擇指南
<點擊查看詳情>
客戶案例
DSS(Cat# 60316ES)
——含硫量16-20%,游離硫<0.2%,模擬人UC模型,安全高效
客戶1:
圖1 結(jié)腸炎H&E染色結(jié)果
客戶來源:南京農(nóng)業(yè)大學
動物類型:C57BL/6小鼠
造模方法:3% (w/v) DSS自由飲用7天
引用自:doi.org/10.1016/j.jnutbio.2020.108438
客戶2:
圖2.結(jié)腸癌H&E染色結(jié)果
客戶來源:暨南大學
動物類型:BALB/c小鼠
造模方法:
1. 10 mg/kg AOM處理小鼠后用純水自由飲1周;
2. 2.5%(w/v)DSS自由飲用1周,換純水自由飲用2周
3. 步驟2重復3次。
引用自:doi: 10.3389/fphar.2020.586885
雨蛙素(Cat# 60321ES)
——十肽分子形式,純度(HPLC)≥97%
客戶3:
圖3.胰腺H&E染色結(jié)果
客戶來源:上海交通大學醫(yī)學院
實驗動物:Balb/c小鼠
造模方法:以1小時間隔腹腔注射7次50 μg/kg雨蛙素,并在最后一次同時注LPS (10 mg/kg)誘導SAP。
引用自:doi.org/10.1016/j. ebiom.2022.103959
STZ(Cat# 60256ES)
客戶4:
圖4.各器官H&E染色結(jié)果
客戶來源:華中科技大學同濟醫(yī)學院
引用自:DOI: 10.1021/acsami.1c24569
部分客戶文獻
[1] Li Zhao, Fei Wang,Zhengwei Cai,et al.Improving drug utilization platform with injectable mucoadhesive hydrogel for treating ulcerative colitis[J].chemical engineering journal.424(2021)130464.IF=16.744
[2] Lingjun Tong, Haining Hao, Zhe Zhang,et al.Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota[J].Theranostics.2021; 11(17): 8570-8586 IF=11.556
[3] Li, Y., Dong, J., Xiao, H., Zhang, S., Wang, B., Cui, M., & Fan, S. Gut commensal derived-valeric acid protects against radiation injuries. Gut Microbes,.2020 .1–18.IF=10.245
[4] Jingjing Gan, Yuxiao Liu, Lingyu Sun,et al.Orally administrated nucleotide-delivery particles from microfluidics for inflammatory bowel disease treatment[J].Applied Materials Today.2021 Dec;25:101231 IF=10.041
[5] JialiDong,YuanLi,HuiwenXiao,et al.Oral microbiota affects the efficacy and prognosis of radiotherapy for colorectal cancer in mouse models[J].Cell reports.2021, 109886.IF=9.423
[6] Xi Z, Ahmad E, Zhang W, et al. Dual-modified nanoparticles overcome sequential absorption barriers for oral insulin delivery. J Control Release. 2022;342:1-13. doi:10.1016/j.jconrel.2021.11.045.IF=9.776
[7] Xu Z, Liu Y, Ma R, et al. Thermosensitive Hydrogel Incorporating Prussian Blue Nanoparticles Promotes Diabetic Wound Healing via ROS Scavenging and Mitochondrial Function Restoration. ACS Appl Mater Interfaces. 2022;14(12):14059-14071. doi:10.1021/acsami.1c24569.IF=9.229
[8] He R, Shi J, Xu D, et al. SULF2 enhances GDF15-SMAD axis to facilitate the initiation and progression of pancreatic cancer. Cancer Lett. 2022;538:215693. doi:10.1016/j.canlet.2022.215693.IF=8.679
[9] Zhang L, Shi J, Du D, et al. Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis. EBioMedicine. 2022;78:103959. doi:10.1016/j.ebiom.2022.103959.IF=8.143
[10]Xuan Zhang, Xia Gao, Xiangzhou Yi, et al. Multi-targeting inulin-based nanoparticles with cannabidiol for effective prevention of ulcerative colitis[J]. Materials Today Bio.2024, 25100965. IF=8.2
<上下滑動查看更多>