重慶市華雅干細(xì)胞技術(shù)有限公司 |
15021010459
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- https://www.ys-bio.cn/
BIO(GSK-3β inhibitor),糖原合成酶激酶抑制劑,BIO-005/025/100
參考價(jià) | 面議 |
- 型號(hào) BIO-005/025/100
- 品牌 StemRD/美國
- 廠商性質(zhì) 代理商
- 產(chǎn)品資料 查看pdf文檔
- 所在地 重慶市
更新時(shí)間:2017-01-07 10:33:07瀏覽次數(shù):1351
聯(lián)系我們時(shí)請(qǐng)說明是化工儀器網(wǎng)上看到的信息,謝謝!
產(chǎn)品編號(hào):BIO-005/025/100
品牌;StemRD
廠家:StemRD
產(chǎn)品規(guī)格:5/25/100mg
儲(chǔ)存條件:-80℃
到貨時(shí)間:2-5天
產(chǎn)品信息
Wnt信號(hào)通路是一個(gè)復(fù)雜的蛋白質(zhì)作用網(wǎng)絡(luò),其功能zui常見于胚胎發(fā)育和癌癥,但也參與成年動(dòng)物的正常生理過程。Wnt信號(hào)通路包括許多可調(diào)控Wnt信號(hào)分子合成的蛋白質(zhì),它們與靶細(xì)胞上的受體相互作用,而靶細(xì)胞的生理反應(yīng)則來源于細(xì)胞和胞外Wnt配體的相互作用。
BIO (6-bromoindirubin-3'-oxime):
a specific GSK3 kinase inhibitor. Inhibition of GSK3-beta results in activation of the canonical WNT pathway leading to the translocation of beta-catenin to the nucleus.
This chemical compound from StemRD is 98.5% pure (HPLC). In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 5.0 micromolar.
Purity:
Greater than 98.5% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity:
In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 5.0 micromolar.
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