ATP合成酶β5抗體 返回列表頁

英文名稱 ATP5B
中文名稱 ATP合成酶β5抗體
別    名 ATP 5B; ATP synthase H+ transporting mitochondrial F1 complex beta polypeptide; ATP Synthase H+ Transporting Mitochondrial F1 Complex Subunit Beta; ATP synthase subunit beta mitochondrial; ATP synthase subunit beta, mitochondrial; ATP5B; ATPB; ATPB_HUMAN; ATPMB; ATPSB; MGC5231; Mitochondrial ATP synthase beta subunit; Mitochondrial ATP Synthase Subunit Beta; Mitochondrial ATP synthetase beta subunit.
ATP合成酶β5抗體    
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 51kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human ATP5B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ATP合成酶β5抗體產(chǎn)品介紹 background:
Mitochondrial ATP synthase is composed of two multi-subunit complexes that utilize an inner membrane electrochemical gradient to catalyze the synthesis of ATP during oxidative phosphorylation. The two multi-subunit complexes are designated F1 and F0, the former of which comprises the soluble catalytic core and the latter of which comprises the membrane-spanning proton channel of ATP synthase. F1 consists of five distinct subunits, designated ATP5A, ATP5B, ATP5C1, ATP5D and ATP5E, while F0 consists of ten subunits, designated ATP5H, ATP5G1, ATP5I, ATP5G2, ATP5J2, ATP5J, ATP5G3, ATP5S, ATP5F1 and ATP5L. ATP5B, also designated ATPMB, ATPSB or mitochondrial ATP synthetase, beta subunit, is a 529 amino acid protein that localizes to the mitochondrial membrane and exists as a subunit of the F0 complex. ATP5B is encoded by a nuclear gene and assembled with the other subunits encoded by both mitochondrial and nuclear genes. The ATP5B gene is activated by members of the Ets family of transcription factors, suggesting that Ets transcription factors are involved in the enhanced expression of the ATP5B gene in highly proliferating cells and in the coordinate transcription of nuclear genes for mitochondrial proteins. ATP5B mRNA levels vary among species through transcriptional control with high expression levels in heart, lower levels in skeletal muscle and the lowest levels in liver and kidney.

Function:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

Subunit:
F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c. Component of an ATP synthase complex composed of ATP5F1, ATP5G1, ATP5E, ATP5H, ATP5I, ATP5J, ATP5J2, MT-ATP6, MT-ATP8, ATP5A1, ATP5B, ATP5D, ATP5C1, ATP5O, ATP5L, USMG5 and MP68

Subcellular Location:
Mitochondrion. Mitochondrion inner membrane. Peripheral membrane protein.

Similarity:
Belongs to the ATPase alpha/beta chains family.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.ATP合成酶β5抗體xy-0745R IGC非洲爪蟾IGC抗體
xy-1031R IFITM1干擾素誘導(dǎo)跨膜蛋白1抗體
xy-0784R IFN-β干擾素β抗體
xym-0388M IFN gamma(F2E4)γ-干擾素/γ-IFN單克隆抗體
xy-0481R IFN gamma干擾素-γ/IFN-γ抗體
xy-0480R IFN gamma干擾素-γ/IFN-γ抗體
xy-0227R IGF1R胰島素樣生長因子I受體抗體
xy-0680R IGF1R胰島素樣生長因子1受體抗體
xy-1108R IGFBP2胰島素樣生長因子結(jié)合蛋白2抗體
xy-0406R IGFBP5胰島素樣生長因子結(jié)合蛋白5抗體
xy-0014R IGF 1胰島素樣生長因子1抗體
xy-0015R IGF II胰島素樣生長因子-II抗體
xy-0698R IL-10白細(xì)胞介素10抗體
xy-0560R IL-13白介素13抗體
xy-1183R IL-17白介素-17抗體
xy-0529R IL-18白細(xì)胞介素-18/干擾素γ誘導(dǎo)因子抗體
xy-0445R IL1RAPL1白介素1受體相關(guān)蛋白樣1前體蛋白抗體
xy-0812R IL-1 Beta白介素1β/IL-1β抗體
xy-1191R IL-2白介素2抗體（大、小鼠）
xym-0389M IL-2(H2E4)白細(xì)胞介素-2單克隆抗體
xy-1193R IL-23白介素-23抗體
xy-0581R IL-4白介素4抗體
xy-0781R IL-6白介素6
xy-0782R IL-6白介素6抗體