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IDO1抗體

抗原
Indoleamine 2,3-Dioxygenase 1 (IDO1)
別名 INDO, ido, indo, IDO, cd107b, IDO1, IDO-1, Ido, Indo
適用
其他選擇 Murine, Human
Human(85),Murine (31),Rat ((Rattus)) (17),Dog (Canine) (16),Bovine (12),Pig (Porcine) (12)
宿主
其他選擇 Mouse
Rabbit(58),Mouse (32),Goat (6),Sheep (1)
克隆類型 (克隆位點)
單克隆 (10.1)
標記
其他選擇 非結(jié)合性
Biotin(2),FITC (2),HRP (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PE (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)
Western Blotting (WB)(75),ELISA (40),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (20),Immunohistochemistry (IHC) (16),Immunofluorescence (IF) (11),Immunofluorescence (Cultured Cells) (IF (cc)) (10),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Flow Cytometry (FACS) (7),Immunocytochemistry (ICC) (5),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (5),Enzyme Immunoassay (EIA) (3),Immunoassay (IA) (3),Immunohistochemistry (Frozen Sections) (IHC (fro)) (3),Immunoprecipitation (IP) (3)
[Pubmed] 1 reference available
規(guī)格 25 μL
發(fā)貨至 中國 (更改)

IDO1抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

顯示 隱藏
免疫原 Anti-IDO1 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with fragment of recombinant human and mouse IDO1 protein followed by hybridoma development.
Immunogen Type: RecombinantProtein
克隆位點 10.1
亞型 IgG3
特異性 Anti-IDO1 was purified from concentrated tissue culture supernate by Protein G chromatography followed by extensive dialysis against the buffer stated above. This antibody is specific for human and mouse IDO1 protein. A BLAST analysis was used to suggest cross-reactivity with IDO1 from human and mouse sources based on 100% homology with the immunizing sequence. Cross-reactivity with IDO1 from other sources has not been determined.
產(chǎn)品特性 Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.
過濾 Sterile filtered

目標詳細情況

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目標詳細情況

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別名 IDO1
背景 Indoleamine 2, 3-dioxygenase1 (IDO1) is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites, resulting in negative effects on T lymphocytes, including proliferation, function and survival. IDO1 may be involved in the suppression of the immune response to tumors, and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy. IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines.
Synonyms: Ido, Indo, Indoleamine 2,3-dioxygenase 1, Indoleamine-pyrrole 2,3-dioxygenase, Ido1, Ido-1
基因ID 3620
NCBI Accession NP_002155
UniProt P14902

使用細節(jié)

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使用細節(jié)

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應(yīng)用備注 Anti-IDO1 antibody has been tested for use in ELISA, Western Blot, IP, IHC, and Flow Cytometry. Specific conditions for reactivity should be optimized by the end user.
說明

Gene Name: Ido1

限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 1.0 mg/mL
緩沖液 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C/-20 °C
儲存方法 Store vial at 4° C prior to restoration.   For extended storage aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing.  Centrifuge product if not compley clear after standing at room temperature.  This product is stable for several weeks atxy-15305R C8orf868號染色體開放閱讀框86抗體
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有效期 12 months