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CLEC7A抗體

抗原
C-Type Lectin Domain Family 7, Member A (CLEC7A)
別名 CLEC7A, BGR, Clecsf12, beta-GR, CANDF4, CLECSF12, DECTIN1, Clec7b, RGD1565140
抗原表位
其他選擇 AA 69-244
C-Term(12),N-Term (8),AA 69-98 (7),AA 69-244 (6),Middle Region (5),AA 1-77 (2),AA 36-127 (1),Center (1),Internal Region (1)
適用
其他選擇 Murine
Human(68),Murine (60),Rat ((Rattus)) (20)
宿主
其他選擇 Rabbit
Rabbit(41),Rat (35),Mouse (32)
克隆類型 (克隆位點(diǎn))
單克隆 (10)
標(biāo)記
其他選擇 PE
FITC(21),PE (14),Biotin (7),APC (3),HRP (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),CF (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PerCP (1)
應(yīng)用范圍
其他選擇 Flow Cytometry (FACS)
Flow Cytometry (FACS)(65),Western Blotting (WB) (28),ELISA (17),Immunoprecipitation (IP) (12),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (Frozen Sections) (IHC (fro)) (8),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8),Immunohistochemistry (IHC) (7),Functional Studies (Func) (4),Immunohistochemistry (Acetone-fixed) (IHC (af)) (4),Immunoassay (IA) (2),Enzyme Immunoassay (EIA) (1),Immunofluorescence (IF) (1),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1)
規(guī)格 50 tests
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CLEC7A抗體

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產(chǎn)品細(xì)節(jié)

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免疫原 Recombinant Mouse Dectin-1 / CLEC7A protein
克隆位點(diǎn) 10
亞型 IgG
特異性 Mouse Dectin-1 / CLEC7A
產(chǎn)品特性 This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Dectin-1 / CLEC7A (rM Dectin-1 / CLEC7A, NP_064392.2, Phe69- Leu244) and conjugated with PE under optimum conditions, the unreacted PE was removed.

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別名 CLEC7A
背景 C-type lectin domain family 7 member A, also known as Dendritic cell-associated C-type lectin 1, Dectin-1, Beta-glucan receptor, C-type lectin superfamily member 12, BGR, CLECSF12, and CLEC7A, is a single-pass type II membrane protein which contains oneC- type lectin domain. CLEC7A (Dectin-1) belongs to the large family of pattern recognition receptors (PRRs) which recognize conserved pathogen-associated molecular patterns (PAMPs). CLEC7A (Dectin-1) is highly expressed in peripheral blood leukocytes and dendritic cells. It is also detected in spleen, bone marrow, lung, muscle, stomach and placenta. CLEC7A (Dectin-1) is a pattern-recognition receptor that predominantly recognizes beta-glucans from fungi, plants and bacteria. CLEC7A (Dectin-1) is implicated in immunological defenses against pathogens that have beta-glucans. CLEC7A (Dectin-1) was identified as the most important receptor for beta-glucan. Recognition of beta-glucan by CLEC7A (Dectin-1) triggers effective immune response, including phagocytosis and proinflammatory factor production, to eliminate infecting fungi. CLEC7A (Dectin-1) is also involved in the adaptive immune response as well as autoimmune diseases and immune tolerance. CLEC7A (Dectin-1) is a small C-type lectin receptor for fungal cell wall beta- glucan. Its homologues in some species, including mouse and human. The sequence of mouse CLEC7A (Dectin-1) is found to be highly homologous to that of the rat. It possesses essential motifs for the recognition of beta-glucan and signal transduction. Mouse CLEC7A (Dectin-1) plays essential roles in immune responses against fungi. .
NCBI Accession NP_064392.2

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應(yīng)用備注 Concentration: 10 μl/Test, 0.1 mg/ml
限制 For Research Use only

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狀態(tài) Liquid
緩沖液 Aqueous solution containing 0.5% BSA and 0.09% sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項(xiàng) Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal
儲(chǔ)存條件 4 °C/-20 °C/-80 °C
儲(chǔ)存方法 This antibody is stable for 12 months from date of receipt when stored at 2 °C - 8 °C.
有效期 12 months

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