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Maleimide-PEG3-TCO; CAS:1609659-01-9

英文名稱(chēng):TCO-PEG3-Maleimide；Trans-Cyclooctene-PEG3-Maleimide

中文名稱(chēng): 反式環(huán)辛烯-三聚乙二醇-馬來(lái)酰亞胺

CAS:1609659-01-9

分 子 式：C26H41N3O8

分 子 量:523.62 g/mol

外    觀：無(wú)色或微黃色的油狀物

溶 解 性：DMSO, DMF, DCM, THF, Chloroform

純    度：>95% (HPLC)

結(jié) 構(gòu) 式：

產(chǎn)品簡(jiǎn)介：

The inverse-electron demand Diels-Alder cycloaddition reaction of trans-Cyclooctenes (TCO) with tetrazines is a bioorthogonal reaction that possesses exceptional kinetics (k > 800 M-1s-1) and selectivity. Such excellent reaction rate constants are unparalleled by any other bioorthogonal reaction pair described to date.
The extremely fast kinetics of this reaction enables rapid conjugation (30 min or less) two low abundance biopolymers (e.g. 5 μM) in aqueous buffered media. The TCO-tetrazine click reaction is the standard in protein-protein conjugation.

其它TCO化合物：

Maleimide-PEG3-TCO; CAS:1609659-01-9