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當前位置:上海信裕生物科技有限公司>>抗體>>一抗>> β淀粉樣蛋白前體蛋白結(jié)合蛋白2抗體
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更新時間:2018-02-15 22:09:01瀏覽次數(shù):471次
聯(lián)系我時,請告知來自 化工儀器網(wǎng)英文名稱 APPBP2
中文名稱 β淀粉樣蛋白前體蛋白結(jié)合蛋白2抗體
別 名 amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein binding protein 2; Amyloid protein-binding protein 2; APBP2_HUMAN; APP BP2; APP-BP2; Appbp2; PAT1; Ara67 Protein interacting with APP tail 1.
β淀粉樣蛋白前體蛋白結(jié)合蛋白2抗體
說 明 書 0.2ml
研究領(lǐng)域 免疫學 神經(jīng)生物學 Alzheimer's
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Zebrafish,
產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
細胞定位 細胞核 細胞漿
性 狀 Lyophilized or Liquid
濃 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human APPBP2
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
β淀粉樣蛋白前體蛋白結(jié)合蛋白2抗體產(chǎn)品介紹 background:
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008].
Function:
May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.
Subunit:
Binds APP.
Subcellular Location:
Nucleus. Cytoplasm
Post-translational modifications:
Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.
Similarity:
Contains 8 TPR repeats.
Database links:
Entrez Gene: 10513 Human
Entrez Gene: 66884 Mouse
Entrez Gene: 303396 Rat
Entrez Gene: 417645 Chicken
Omim: 605324 Human
SwissProt: Q92624 Human
SwissProt: Q9DAX9 Mouse
SwissProt: A5HK05 Rat
Unigene: 84084 Human
Unigene: 271997 Mouse
Unigene: 104856 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.β淀粉樣蛋白前體蛋白結(jié)合蛋白2抗體xy-4539R IL-6白介素6
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