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緩激肽B2受體抗體

參   考   價: 1650

訂  貨  量: ≥1 

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更新時間:2018-01-20 05:29:26瀏覽次數(shù):466次

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BDKRB2
WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
not yet tested in other applications.
optimal dilutions/c

英文名稱 BDKRB2
中文名稱 緩激肽B2受體抗體
別    名 B2; B2 bradykinin receptor; B2BKR; B2BRA; B2R; BDKR B2; BDKRB 2; Bdkrb2; BK 2; BK 2 receptor; BK R2; BK2; BK2 receptor; BK2R; BKR 2; BKR2; BR B2; Bradykinin receptor b2; Bradykinin receptor beta 2; BRB 2; BRB2; DKFZp686O088; Kinin B2 Bradykinin receptor beta 2; B2R.
緩激肽B2受體抗體    
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Bdkrb2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Bradykinin increases vascular permeability, dilates blood vessels, contracts non-vascular smooth muscle, and causes pain. This product detects a receptor for bradykinin. The receptor is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Bradykinin B2 receptor expression has been reported in blood, brain, eye, kidney, liver, lung,prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, kidney, lung, placenta, and thyroid libraries.

Function:
Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Subunit:
Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Ubiquitous. Widespread in normal smooth muscle tissue and neurons.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB2 sub-subfamily.

Gene ID:
624

Database links:

Entrez Gene: 624 Human

Entrez Gene: 12062 Mouse

Omim: 113503 Human

SwissProt: P30411 Human

SwissProt: P32299 Mouse

Unigene: 654542 Human

Unigene: 726620 Human

Unigene: 390475 Mouse



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