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Fibrinogen 抗體 

抗原
Fibrinogen
別名 fib2, MGC53620, fibrinogen, sb:cb892, wu:fa55c12, wu:fb20e08, wu:fb59b03, wu:fi39d04, zgc:92117
適用
其他選擇 Human
Human(229),Murine (52),Rat (Rattus) (30),Rabbit (22),Bovine (17),Pig (Porcine) (15),Dog (Canine) (13),General (1)
宿主
其他選擇 Rabbit
Rabbit(148),Mouse (84),Goat (83),Sheep (41),Chicken (7),Rat (2)
克隆類型
多克隆抗體
標記
其他選擇 非結(jié)合性
Biotin(35),HRP (32),FITC (31),Alexa Fluor 555 (5),Alexa Fluor 647 (5),Cy3 (5),Cy5 (5),Cy5.5 (5),Cy7 (5),Alexa Fluor 488 (4)
應(yīng)用范圍
其他選擇 Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
ELISA(212),Western Blotting (WB) (173),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (47),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (43),Immunofluorescence (IF) (34),Immunoelectrophoresis (IEP) (28),Immunocytochemistry (ICC) (25),Immunohistochemistry (IHC) (25),Immunohistochemistry (Frozen Sections) (IHC (fro)) (24),ELISA (Detection) (20),Radioimmunoassay (RIA) (19),Immunodiffusion (ID) (15),Immunoprecipitation (IP) (15),Enzyme Immunoassay (EIA) (13),Radial Immunodiffusion (RID) (9),ELISA (Capture) (6),Immunoassay (IA) (4),Flow Cytometry (FACS) (3),Magnetic Beads (MB) (3),Protein Assay (PrA) (2),Affinity Chromatography (AC) (1),Blocking Reagent (BR) (1),Electrophoresis (EP) (1),Gel Shift (GS) (1),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1),Immunomicroscopy (IM) (1),Immunoturbidimetry (IT) (1),Labeling (Lbl) (1),Nephelometry (Neph) (1),Ouchterlony Double Diffusion (ODD) (1)
規(guī)格 100 μL
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Fibrinogen 抗體 

目標詳細情況

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別名 Human Fibrinogen
背景 Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3?mg/mL. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
分子量 340kDa
基因ID 2243

使用細節(jié)

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使用細節(jié)

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 應(yīng)用備注 WB(1:100-500)
IHC-P(1:100-500)
IF(IHC-P)(1:100-500)
限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 1 μg/μL
緩沖液 Aqueous buffered solution containing 100?μg/mL BSA, 50?% glycerol and 0.09?% sodium azide.
儲存液 Sodium azide
 注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 -20 °C
儲存方法 Store at -20 °C for 12 months.
有效期 12 months

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