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抗原
phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A)
別名 PLA2G4A, pla2g4, CPLA2, PLA2G4, Pla2g4, cPLA2, cPLA2alpha, cPLA2-alpha, Pla2c, PLA2, PLA2G1B
抗原表位
其他選擇 AA 513-541, Center
pSer505(18),Internal Region (10),C-Term (5),AA 1-110 (2),AA 1-749 (2),AA 563-749 (2),AA 1-111 (1),AA 1-178 (1),AA 1-263 (1),AA 336-664 (1),AA 471-520 (1),AA 513-541 (1),AA 520-549 (1),Asn499 (1),Middle Region (1),N-Term (1),Ser505 (1),Thr234 (1)
適用
其他選擇 Human
Human(67),Murine (34),Rat ((Rattus)) (31),Chicken (11),Dog (Canine) (11),Pig (Porcine) (11)
宿主
其他選擇 Rabbit
Rabbit(58),Mouse (5),Goat (4),Sheep (2)
克隆類型 (克隆位點)
多克隆 (RB21320)
標記
其他選擇 非結(jié)合性
Biotin(5),FITC (3),HRP (3),Alexa Fluor 350 (2),Alexa Fluor 488 (2),Alexa Fluor 555 (2),Alexa Fluor 647 (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2),APC (1),Alkaline Phosphatase (AP) (1),PE (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
Western Blotting (WB)(49),ELISA (29),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (19),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15),Immunofluorescence (IF) (12),Immunohistochemistry (IHC) (12),Immunocytochemistry (ICC) (7),Flow Cytometry (FACS) (4),Immunohistochemistry (Frozen Sections) (IHC (fro)) (4),Enzyme Immunoassay (EIA) (2),Immunoprecipitation (IP) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (1)
[Pubmed] 2 references available
規(guī)格 400 μL
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發(fā)貨時間 9至13個工作日
PLA2G4A抗體
產(chǎn)品細節(jié)
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產(chǎn)品細節(jié)
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免疫原 This PLA2G4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-541 AA from the Central region of human PLA2G4A.
克隆位點 RB21320
亞型 Ig
特異性 This PLA2G4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 520~549 amino acids from the Center region of human PLA2G4A.
預(yù)測反應(yīng) Chicken,Mouse (Murine),Rat (Rattus),Rabbit,Zebrafish
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.
目標詳細情況
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目標詳細情況
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別名 PLA2G4A
背景 PLA2G4A is a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into plaet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
Synonyms: Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA, Phospholipase A2, Phosphatidylcholine 2-acylhydrolase, Lysophospholipase, PLA2G4, CPLA2, PLA2G4A
分子量 85211 DA
基因ID 5321
UniProt P47712
研究領(lǐng)域 Neurology
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使用細節(jié)
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應(yīng)用備注 WB = 1:1000, IHC = 1:10-50, IF = 1:10-50, FACS = 1:10-50
限制 For Research Use only
貯存及處理
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貯存及處理
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狀態(tài) Liquid
濃度 0.41 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲存條件 4 °C/-20 °C
儲存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months
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