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MAVS抗體

抗原
Mitochondrial Antiviral Signaling Protein (MAVS)
別名 VISA, HISPPD2A, IP6K, IPS1, VIP1, hsVIP1, CARDIF, IPS-1, D430028G21Rik, Visa, cardif
抗原表位
其他選擇 C-Term, AA 477-505
N-Term(23),C-Term (11),AA 1-30 (9),AA 476-505 (7),Middle Region (5),Internal Region (3),AA 150-200 (2),AA 160-450 (2),AA 1-540 (1),AA 250-300 (1),AA 477-505 (1),Center (1)
適用
其他選擇 Human
Human(71),Murine (43),Rat ((Rattus)) (33),Bovine (13)
宿主
其他選擇 Rabbit
Rabbit(78),Mouse (2)
克隆類型 (克隆位點(diǎn))
多克隆 (RB33921)
標(biāo)記
其他選擇 非結(jié)合性
Biotin(3),FITC (3),HRP (3),APC (2),Alkaline Phosphatase (AP) (2),PE (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應(yīng)用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(69),ELISA (30),Immunohistochemistry (IHC) (19),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (19),Immunofluorescence (IF) (10),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunocytochemistry (ICC) (5),Immunoprecipitation (IP) (5),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (4),Enzyme Immunoassay (EIA) (2),Immunoassay (IA) (1)
[Pubmed] 4 references available
規(guī)格 400 μL
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 9至13個(gè)工作日

MAVS抗體

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 This MAVS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-505 AA from the C-terminal region of human MAVS.
克隆位點(diǎn) RB33921
亞型 Ig
特異性 This MAVS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human MAVS.
純化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 MAVS
背景 Double-stranded RNA viruses are recognized in a cell type-dependent manner by the transmembrane receptor TLR3 (MIM 603029) or by the cytoplasmic RNA helicases MDA5 (MIM 606951) and RIGI (ROBO3, MIM 608630). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK, MIM 600664) and IKKB (IKBKB, MIM 603258), which activate NFKB (see MIM 164011), or TBK1 (MIM 604834) and IKKE (IKBKE, MIM 605048), which activate IRF3 (MIM 603734). Activated IRF3 and NFKB induce transcription of IFNB (IFNB1, MIM 147640). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1, MIM 607601). For RIGI, the intermediary protein is mitochondria-bound IPS1 (Sen and Sarkar, 2005 [PubMed 16239922]).
Synonyms: Mitochondrial antiviral-signaling protein,MAVS,IPS1, KIAA1271, VISA
分子量 56528 DA
基因ID 57506
NCBI Accession NP_065797
UniProt Q7Z434
研究領(lǐng)域 Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications

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使用細(xì)節(jié)

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應(yīng)用備注 WB = 1:1000
限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Liquid
濃度 0.5 mg/mL
緩沖液 PBS with 0.09 % (W/V) sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C/-20 °C
儲(chǔ)存方法 MAVS Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
有效期 6 months

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