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當(dāng)前位置:上海信裕生物科技有限公司>>抗體>>一抗>> CYP11A1抗體
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更新時(shí)間:2018-01-21 09:02:53瀏覽次數(shù):684次
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抗原
Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1)
別名 CYP11A, CYP11A1, CYPXIA1, P450SCC, Cyp11a, Cypxia1, D9Ertd411e, P450scc, Scc, cscc, P450(scc), SSC
抗原表位
其他選擇 Middle Region
C-Term(14),N-Term (5),AA 1-521 (2),AA 241-481 (1),AA 398-447 (1)
適用
其他選擇 Human
Human(59),Murine (31),Rat ((Rattus)) (31),Bovine (12),Dog (Canine) (12),Pig (Porcine) (12)
宿主
其他選擇 Rabbit
Rabbit(59),Mouse (1)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(3),FITC (3),HRP (3),Alexa Fluor 350 (2),Alexa Fluor 488 (2),Alexa Fluor 555 (2),Alexa Fluor 647 (2),Cy3 (2),Cy5 (2),Cy5.5 (2),Cy7 (2)
應(yīng)用范圍
其他選擇 Immunohistochemistry (IHC), Western Blotting (WB)
Western Blotting (WB)(42),ELISA (21),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (20),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9),Immunohistochemistry (IHC) (4),Immunoassay (IA) (2),Enzyme Immunoassay (EIA) (1),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1)
[Pubmed] 1 reference available
規(guī)格 50 μg
發(fā)貨至 中國 (更改)
發(fā)貨時(shí)間 9至12個(gè)工作日
CYP11A1抗體
產(chǎn)品細(xì)節(jié)
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產(chǎn)品細(xì)節(jié)
顯示 隱藏
免疫原 Synthetic peptide directed towards the middle region of human CYP11A1
序列 LRQKGSVHHD YRGILYRLLG DSKMSFEDIK ANVTEMLAGG VDTTSMTLQW
預(yù)測(cè)反應(yīng) Human : 100 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against CYP11A1. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Affinity Purified
目標(biāo)詳細(xì)情況
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目標(biāo)詳細(xì)情況
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別名 CYP11A1
背景 CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP11A1 localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
分子量 57 kDa
基因ID 1583
NCBI Accession NM_000781, NP_000772
UniProt P05108
研究領(lǐng)域 Cancer, Metabolism
使用細(xì)節(jié)
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使用細(xì)節(jié)
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應(yīng)用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明
Antigen size: 521 AA
限制 For Research Use only
貯存及處理
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貯存及處理
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狀態(tài) Lyophilized
溶解方式 Add 50 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項(xiàng) Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 -20 °C
儲(chǔ)存方法 For longer periods of storage, store at -20 °C
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