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FAS 抗體

抗原
Fas (TNF Receptor Superfamily, Member 6) (FAS)
別名 AI196731, APO1, APT1, CD95, TNFR6, Tnfrsf6, lpr, TNFRSF6, ALPS1A, APO-1, FAS1, FASTM, A630082H08Rik, FAS
抗原表位
其他選擇 AA 1-169
pTyr291(33),C-Term (30),Extracellular Domain (30),Internal Region (13),N-Term (13),pTyr232 (13),AA 1-173 (12),AA 20-119 (10),AA 1-169 (7),AA 323-327 (6),Tyr291 (6),AA 1-170 (4),AA 1-335 (4),Cytoplasmic Domain (4),AA 196-220 (3),AA 185-211 (2),AA 21-170 (2),AA 22-169 (2),AA 26-173 (2),AA 29-44 (2),Center (2),Middle Region (2),AA 153-248 (1),AA 17-173 (1),AA 188-319 (1),AA 191-220 (1),AA 21-165 (1),AA 22-172 (1),AA 257-306 (1),AA 281-330 (1),AA 285-335 (1),AA 30-252 (1),AA 36-236 (1),AA 87-109 (1),Intracellular (1),Isoform 1 (1),Leu315 (1),Lys259 (1),Lys287 (1),Ser15 (1),pThr291 (1)
適用
其他選擇 Murine
Human(498),Murine (95),Rat ((Rattus)) (65),Pig (Porcine) (12),Monkey (10),Zebrafish (4),Bovine (2),Cat (1),Dog (Canine) (1),Rabbit (1)
宿主
其他選擇 Rabbit
Mouse(322),Rabbit (250),Rat (8),Goat (6),Hamster (6),Chicken (4)
克隆類型 (克隆位點)
單克隆 (4)
標記
其他選擇 FITC
FITC(53),Biotin (45),PE (40),APC (15),HRP (8),Alexa Fluor 350 (4),Alexa Fluor 488 (4),Alexa Fluor 555 (4),Alexa Fluor 647 (4),Cy3 (4),Cy5 (4),Cy5.5 (4),Cy7 (4),Alkaline Phosphatase (AP) (2),SPRD (2),Cy5,PE (1),Magnetic Particles (1),PE,Cy5 (1),Sepharose (1)
應用范圍
其他選擇 Flow Cytometry (FACS)
Flow Cytometry (FACS)(265),Western Blotting (WB) (235),ELISA (142),Immunohistochemistry (IHC) (86),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (83),Immunoprecipitation (IP) (72),Immunohistochemistry (Frozen Sections) (IHC (fro)) (62),Immunofluorescence (IF) (40),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (40),Functional Studies (Func) (31),Immunocytochemistry (ICC) (31),Enzyme Immunoassay (EIA) (13),Dot Blot (DB) (12),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (9),Blocking Antibody (Inhibition) (7),Neutralization (Neut) (7),Activation (Act) (3),Apoptosis Blocking (AB) (3),Apoptosis Induction (AI) (3),Immunoassay (IA) (3),Fluorescence Microscopy (FM) (2),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2),Intracellular Staining (ICS) (2),Proximity Ligation Assay (PLA) (2),Blocking Reagent (BR) (1)
規(guī)格 50 tests
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FAS 抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

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免疫原 Recombinant Mouse CD95 / APO-1 / TNFRSF6 / FAS protein
克隆位點 4
亞型 IgG
特異性 Mouse CD95 / APO-1 / TNFRSF6 / FAS
產(chǎn)品特性 This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD95 / APO-1 / TNFRSF6 / FAS (rM CD95 / APO-1 / TNFRSF6 / FAS, NP_032013.2, Met1-Arg169) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

目標詳細情況

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目標詳細情況

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別名 FAS
背景 Fas, also known as APO-1, CD95 and TNFRSF6, is a member of the tumor necrosis factor (TNF) / nerve growth factor (NGF) receptor superfamily. Fas is highly expressed on the surface of a number of cell types including epithelial cells, hepatocytes, activated mature lymphocytes and other tumor cells. This receptor contains a death domain and has been shown to play a central role in the physiological regulation of programmed cell death (PCD, apoptosis) upon ligation of Fas ligand (Fas-L). This Fas receptor has been reported to be involved in the activation of NF-kappaB, MAPK3/ERK1, MAPK8/JNK, and the alternate pathways for CTL-mediated cytotoxicity. Accordingly, this protein is implicated in the pathogenesis of various malignancies and diseases of the immune system. Multiple Fas isoforms are derived from alternative spliced transcript variants, and among which, a soluble form lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoforms.
NCBI Accession NP_032013.2

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應用備注 Concentration: 5 μl/Test, 0.1 mg/ml
限制 For Research Use only

貯存及處理

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狀態(tài) Liquid
緩沖液 Aqueous solution containing 0.5% BSA and 0.09% sodium azide
儲存液 Sodium azide
注意事項 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項 Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal
儲存條件 4 °C/-20 °C/-80 °C
儲存方法 This antibody is stable for 12 months from date of receipt when stored at 2 °C - 8 °C.
有效期 12 months

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