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PIGR抗體

抗原
Polymeric Immunoglobulin Receptor (PIGR)
別名 DKFZp469G1013, RNPIGR2, pIgA-R
抗原表位
其他選擇 AA 1-638, Ser365Gly-Mutant
C-Term(9),AA 1-645 (6),AA 1-638 (5),Ser365Gly-Mutant (5),AA 135-237 (3),AA 180-459 (2),AA 353-457 (2),AA 462-561 (2),AA 646-672 (2),Cytoplasmic Domain (2),Extracellular Domain (2),Internal Region (2),AA 180-429 (1),AA 19-120 (1),AA 21-130 (1),AA 250-341 (1),AA 343-447 (1),AA 352-457 (1),AA 461-560 (1),AA 463-563 (1),AA 652-681 (1)
適用
其他選擇 Human
Human(43),Murine (26),Bovine (23),Rat ((Rattus)) (17),Dog (Canine) (12)
宿主
其他選擇 Rabbit
Rabbit(68),Mouse (3),Rat (2)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
Biotin(11),FITC (3),HRP (3),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),PE (1)
zui低檢測(cè)濃度 0.00245 ng/well
應(yīng)用范圍
其他選擇 ELISA
Western Blotting (WB)(47),ELISA (43),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (26),Immunocytochemistry (ICC) (16),Immunohistochemistry (Frozen Sections) (IHC (fro)) (14),Immunohistochemistry (IHC) (14),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunofluorescence (IF) (5),Flow Cytometry (FACS) (3),Enzyme Immunoassay (EIA) (1)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國(guó) (更改)

PIGR抗體

產(chǎn)品細(xì)節(jié)

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產(chǎn)品細(xì)節(jié)

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亞型 IgG
特異性 Human PIGR / Poly-Ig receptor
產(chǎn)品特性 Produced in rabbits immunized with purified, recombinant Human PIGR extracellular domain (rh PIGR, NP_002635.2, Met 1-Arg 638). Total IgG was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過(guò)濾 0.2 μm filtered

目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 PIGR
背景 Polymeric immunoglobulin receptor, also known as,PIGR, is a member of the immunoglobulin superfamily,and a,Fc receptor. The ectodomain of this receptor consists of five units with homology to the variable units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions. PIGR is expressed on several glandular epithelia including those of liver and breast. The deduced amino-acid sequence has a length of 764 residues and shows an overall similarity of 56% and 64% with the rabbit and rat counterpart. PIGR mediates transcellular transport of polymeric immunoglobulin molecules, and thus facilitates the secretion of,IgA,and,IgM. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment of PIGR.
NCBI Accession NP_002635.2
研究領(lǐng)域 Immunology

使用細(xì)節(jié)

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA ELISA: 0.5-1.0 μg/mL This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human PIGR. The detection limit for Human PIGR is 0.00245 ng/well.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲(chǔ)存液 Without preservative
注意事項(xiàng) Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲(chǔ)存條件 4 °C/-20 °C/-80 °C
儲(chǔ)存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 months

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