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CD200抗體

參   考   價: 1800

訂  貨  量: ≥1 

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更新時間:2018-02-02 22:30:32瀏覽次數(shù):371次

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CD200抗體的概念:
Z初有人用電泳證明血清中抗體活性在γ球蛋白部分,故曾把抗體統(tǒng)稱為丙種(γ)球蛋白。后來發(fā)現(xiàn),抗體并不都在γ區(qū);并且位于γ區(qū)的球蛋白,也不一定都具有抗體活性,規(guī)格:0.1ml/100?g、0.2ml/200?g

CD200抗體

抗原
CD200 Molecule (CD200)
別名 CD200, MOX2, DKFZp459C0716, ox2g, Mox2, OX2, MOX1, MRC, OX-2, Cspmo2, MRCOX2
抗原表位
其他選擇 AA 1-232
AA 1-232(13),C-Term (13),AA 182-211 (7),AA 31-232 (3),AA 183-211 (2),AA 1-269 (1),AA 34-124 (1),Internal Region (1)
適用
其他選擇 Human
Murine(78),Human (76),Rat ((Rattus)) (68),Bovine (2),Dog (Canine) (2),Guinea Pig (2),Pig (Porcine) (2),Rabbit (2),Horse (Equine) (1)
宿主
其他選擇 Rabbit
Mouse(98),Rat (54),Rabbit (39),Goat (3)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
FITC(36),PE (33),Biotin (26),APC (3),Alexa Fluor 647 (3),HRP (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
zui低檢測濃度 0.00245 ng/well
應(yīng)用范圍
其他選擇 ELISA
Flow Cytometry (FACS)(156),Immunohistochemistry (Frozen Sections) (IHC (fro)) (36),ELISA (31),Western Blotting (WB) (26),Immunohistochemistry (IHC) (17),Immunoprecipitation (IP) (17),Immunohistochemistry (Acetone-fixed) (IHC (af)) (11),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7),Enzyme Immunoassay (EIA) (3),Functional Studies (Func) (2),Immunoassay (IA) (1),Immunocytochemistry (ICC) (1),Neutralization (Neut) (1)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國 (更改)

CD200抗體

產(chǎn)品細節(jié)

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產(chǎn)品細節(jié)

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亞型 IgG
特異性 Human CD200 / OX-2
產(chǎn)品特性 Produced in rabbits immunized with purified, recombinant Human CD200 (rh CD200, NP_005935.4, Met 1-Gly 232). Total IgG was purified by Protein A affinity chromatography.
純化方法 Affinity Purified
過濾 0.2 μm filtered

目標(biāo)詳細情況

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目標(biāo)詳細情況

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別名 CD200
背景 CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through the CD200:CD200R axis have been shown to play an important role in the regulation of anti-tumor immunity, and overexpression of CD200 has been reported in a number of malignancies, including CLL, as well as on cancer stem cells. The role of CD200-CD200R signaling in immune regulation of the central nervous system has become a popular field of research in recent years. Many studies have shown that there is a close correlation between CD200-CD200R, microglia activation, and Parkinson's disease (PD). The ability of CD200 to suppress myeloid cell activation is critical for maintaining normal tissue homeostasis but may also enhance the survival of migratory neoplastic cells. CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 has been characterized as an important immunoregulatory molecule, increased expression of which can lead to decreased transplant rejection, autoimmunity, and allergic disease. Elevated CD200 expression has been reported to be associated with poor prognosis in a number of human malignancies. In addition, CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
NCBI Accession NP_005935.4
研究領(lǐng)域 CD Antigens, Surface Receptors of Immune Cells

使用細節(jié)

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使用細節(jié)

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應(yīng)用備注 ELISA ELISA: 0.5-1.0 μg/mL This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect Human CD200. The detection limit for Human CD200 is 0.00245 ng/well.
限制 For Research Use only

貯存及處理

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貯存及處理

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緩沖液 PBS with 5% trehalose
儲存液 Without preservative
注意事項 Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
儲存條件 4 °C/-20 °C/-80 °C
儲存方法 This antibody can be stored at 2 °C-8 °C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 °C to -70 °C.
有效期 12 monthsxy-15016R C1orf1291號染色體開放閱讀框129抗體
xy-15017R C1orf1301號染色體開放閱讀框130抗體
xy-15018R C1orf1311號染色體開放閱讀框131抗體
xy-15019R C1orf1351號染色體開放閱讀框135抗體
xy-15021R C1orf1411號染色體開放閱讀框141抗體
xy-15022R C1orf1441號染色體開放閱讀框144抗體
xy-12464R alpha COP ICOPA蛋白抗體
xy-15045R C1orf1851號染色體開放閱讀框185抗體
xy-15969R phospho-alpha B Crystallin (Ser19)磷酸化熱休克蛋白β5/α晶狀體球蛋白B/αB-crystallin抗體
xy-12970R phospho-alpha B Crystallin (Ser45)磷酸化α晶狀體球蛋白B/αB-crystallin抗體
xy-12971R phospho-alpha B Crystallin (Ser53)磷酸化熱休克蛋白β5/α晶狀體球蛋白B/αB-crystallin抗體
xy-15034R C1orf1671號染色體開放閱讀框167抗體
xy-15035R C1orf168 1號染色體開放閱讀框168抗體
xy-15036R C1orf1701號染色體開放閱讀框170抗體
xy-15037R C1orf1721號染色體開放閱讀框172抗體
xy-15038R C1orf173 1號染色體開放閱讀框173抗體
xy-15039R C1orf1741號染色體開放閱讀框174抗體
xy-15040R C1orf1771號染色體開放閱讀框177抗體
xy-15041R C1orf180 1號染色體開放閱讀框180抗體
xy-15043R C1orf182 1號染色體開放閱讀框182抗體
xy-15044R C1orf1831號染色體開放閱讀框183抗體
xy-15047R C1orf1871號染色體開放閱讀框187抗體
xy-15048R C1orf189 1號染色體開放閱讀框189抗體
xy-15049R C1ORF1901號染色體開放閱讀框190抗體
xy-15051R C1orf1921號染色體開放閱讀框192抗體
xy-15052R C1orf1941號染色體開放閱讀框194抗體
xy-15054R C1orf1981號染色體開放閱讀框198抗體
xy-15057R C1orf211號染色體開放閱讀框21抗體

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