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CD82抗體 

抗原
CD82 Molecule (CD82)
別名 AA682076, AL023070, C33, IA4, Kai1, Tspan27, 4F9, GR15, KAI1, R2, SAR2, ST6, TSPAN27
抗原表位
其他選擇 C-Term
C-Term(30),AA 111-228 (6),AA 238-267 (6),AA 1-267 (2),AA 239-267 (2),AA 205-267 (1),AA 253-267 (1),Internal Region (1),Middle Region (1)
適用
其他選擇 Human, Murine, Rat ((Rattus))
Human(96),Murine (36),Rat ((Rattus)) (28),Bovine (12),Dog (Canine) (12),Pig (Porcine) (12),Virus (1)
宿主
其他選擇 Rabbit
Rabbit(69),Mouse (31)
克隆類型
多克隆
標(biāo)記
其他選擇 非結(jié)合性
PE(5),Biotin (4),FITC (4),HRP (3),APC (1),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Alkaline Phosphatase (AP) (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1),Magnetic Particles (1),Sepharose (1)
應(yīng)用范圍
其他選擇 Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB)(57),Flow Cytometry (FACS) (35),ELISA (32),Immunohistochemistry (IHC) (30),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (19),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Immunoprecipitation (IP) (8),Immunohistochemistry (Frozen Sections) (IHC (fro)) (7),Functional Studies (Func) (4),Immunocytochemistry (ICC) (3),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (3),Enzyme Immunoassay (EIA) (1),Immunofluorescence (IF) (1),Immunohistochemistry (Acetone-fixed) (IHC (af)) (1),Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (1),Proximity Ligation Assay (PLA) (1)
[Pubmed] 4 references available
規(guī)格 0.1 mg
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 29至35個(gè)工作日

CD82抗體 

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產(chǎn)品細(xì)節(jié)

顯示 隱藏
免疫原 KAI1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human KAI1.
亞型 IgG
特異性 This antibody detects CD82 at C-term.
交叉反應(yīng) （詳細(xì)） Species reactivity (tested):Human, Mouse
純化方法 Peptide affinity chromatography

 目標(biāo)詳細(xì)情況

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目標(biāo)詳細(xì)情況

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別名 CD82
背景 KAI1 was initially identified from a T-cell activation study as a four-transmembrane protein that plays an accessory role in T-cell activation, and was later determined to act as a cancer metastasis suppressor gene. This protein is ubiquitously expressed at moderate to high levels in most tissues, but its expression is downregulated during tumor progression. The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients. Recently, KAI1 was found to interact with DARC, the Duffy antigen for chemokines using a yeast two hybrid screen. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to the tumor cells, while tumor cells that have lost KAI1 expression can proliferate and potentially give rise to metastases. At least two isoforms of KAI1 are known to exist.Synonyms: C33 antigen, IA4, Inducible membrane protein R2, KAI1, Kangai-1, Metastasis suppressor Kangai-1, SAR2, ST6, Suppressor of tumorigenicity protein 6, TSPAN27, Tetraspanin-27
基因ID 3732
NCBI Accession NP_002222
UniProt P27701
研究領(lǐng)域 Cancer, Transcription Factors, CD Antigens, Adaptive Immunity, Surface Receptors of Immune Cells

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使用細(xì)節(jié)

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應(yīng)用備注 ELISA. Western blot: 0.5 - 1?μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

貯存及處理

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緩沖液 PBS containing 0.02?% sodium azide
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事項(xiàng) Avoid repeated freezing and thawing.
儲(chǔ)存條件 4 °C/-20 °C

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