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抗腫瘤蛋白ANUP抗體

英文名稱 ANUP
中文名稱 抗腫瘤蛋白ANUP抗體
別    名 Anti neoplastic urinary protein; ANUP; ARS; ARS component B; ARS(component B) 81/S; ArsB; LY6LS; Lymphocyte antigen 6 like secreted; MDM; Results in cobblestone changes in the skin of the palm; Secreted Ly 6/uPAR related protein 1; Secreted LY6/PLAUR domain containing 1; Secreted Ly6/uPAR related protein 1; SLURP-1; SLURP1; SLUR1_HUMAN.
  
說 明 書 0.2ml  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  細(xì)胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 9kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLURP1/ANUP
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
SLURP1, also known as MDM, ARS, ANUP (anti-neoplastic urinary protein), LY6LS or ArsB (ARS component B), is a 103 amino acid secreted protein that exists as a homodimer possessing antitumor activity. Found in esophagus, stomach, exocervix, gums, urine, sweat, saliva, plasma and tears, SLURP1 is most highly expressed in the acrosyringium of the granular layer of skin, where it helps maintain the structure of the keratinocyte layers of the skin. Also considered a marker for late skin differentiation, SLURP1 contains one UPAR/Ly6 domain and is the cause of an autosomal recessive disorder of the skin known as Mal de Meleda (MDM). MDM Is characterized by nail abnormalities, keratotic skin lesions, transgressive palmoplantar keratoderma (PPK), perioral erythema and may sometimes include hyperhidrosis.

Function:
Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. 

Subunit:xy-6466R    PRDM1B淋巴細(xì)胞誘導(dǎo)成熟蛋白1抗體
xy-5179R    phospho-PTPRA(Tyr798)磷酸化酪氨酸磷酸酶α抗體
xy-3969R    PRKAR1蛋白激酶A調(diào)節(jié)亞基a1抗體
xy-5175R    phospho-PTPRA (Ser180)磷酸化酪氨酸磷酸酶α抗體
xy-9039R    PDZD5APDZ結(jié)構(gòu)域PDZK5A蛋白抗體
xy-5423R    PPAP2A磷酸脂磷酸水解酶1抗體
xy-4592R    P14ARF抑癌基因p16/p14/P19抗體
xy-9187R    PTPH1蛋白酪氨酸磷酸酶H1抗體
xy-5587R    phospho-PI 3 Kinase p110 delta (Tyr524)磷酸化磷脂酰肌醇激酶催化亞單位D抗體
xy-5643R    phospho-RAD9(Ser277)磷酸化細(xì)胞周期檢查控制蛋白質(zhì)抗體
xy-7128R    Perforin穿孔素抗體
xy-13674R    PALM3PALM3抗體
xy-5107R    PON1芳香酯酶1(對氧磷酶)抗體
xy-5108R    PNPO磷酸吡哆醇氧化酶抗體
xy-5565R    phospho-PRKCB(Ser660)磷酸化蛋白激酶C抗體
xy-5566R    phospho-PRKCB(Ser642)磷酸化蛋白激酶C抗體
xy-5567R    Phospho-PTEN(Ser385)磷酸化腫瘤抑制基因PTEN抗體
xy-5570R    phospho-PI3KCA(Tyr317)磷酸化磷脂酰肌醇激酶催化亞單位A抗體
xy-5571R    phospho-PIK3R1(Tyr467)磷酸化磷脂酰肌醇激酶抗體
xy-5572R    phospho-PIK3R1(Tyr556)磷酸化磷脂酰肌醇激酶抗體
xy-5573R    phospho-PRKCA(Ser657+Tyr658)磷酸化蛋白激酶C抗體
xy-5574R    phospho-PRKCA(Thr637)磷酸化蛋白激酶C抗體
xy-5575R    phospho-AMPK alpha 2 (Ser173)磷酸化腺苷單磷酸活化蛋白激酶α2抗體
xy-4158R    SHP1蛋白酪氨酸磷酸酶1C抗體
xy-5577R    phospho-PTPN6(Tyr536)磷酸化蛋白酪氨酸磷酸酶1C抗體
xy-5578R    phospho-PTPN6(Ser591)磷酸化蛋白酪氨酸磷酸酶1C抗體
xy-4159R    PI 3 Kinase Class 3磷脂酰肌醇激酶3催化亞單位3抗體
xy-5580R    phospho-PIK3C3(Ser676)磷酸化磷脂酰肌醇激酶3催化亞單位3抗體
xy-5581R    phospho-PIK3C3(Ser164)磷酸化磷脂酰肌醇激酶3催化亞單位3抗體
xy-5585R    phospho-PRKCQ(Thr538)磷酸化蛋白激酶C theta抗體
xy-4160R    PI 3 Kinase p85 beta磷脂酰肌醇激酶p85β抗體
xy-5582R    phospho-PIK3R2(Tyr467)磷酸化磷脂酰肌醇激酶p85β抗體
xy-5586R    phospho-PPM1A(Ser375)磷酸化蛋白磷酸酶2C亞型α抗體