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磷酸化突觸融合蛋白1抗體

英文名稱 phospho-Syntaxin 1a(Ser14)
中文名稱 磷酸化突觸融合蛋白1抗體
別    名 Syntaxin 1a (phospho S14); Syntaxin 1a (phospho Ser14); p-Syntaxin 1a (Ser14); HPC 1; Neuron specific antigen HPC1; Neuron-specific antigen HPC-1; OTTHUMP00000174615; OTTHUMP00000174616; OTTHUMP00000174617; OTTHUMP00000174618; P35-1; STX1; STX1A; STX1A_HUMAN; SYN1A; Syntaxin 1A (brain); Syntaxin 1A brain; Syntaxin-1A; Syntaxin-1A.

說 明 書 0.1ml  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  轉(zhuǎn)運蛋白  結(jié)合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Syntaxin 1a around the phosphorylation site of Ser14
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed PubMed
產(chǎn)品介紹 background:
Syntaxin 1a is potentially involved in docking of synaptic vesicles at presynaptic active zones and may play a critical role in neurotransmitter exocytosis. Haploinsufficiency of STX1A may be the cause of certain cardiovascular and musculo skeletal abnormalities observed in Williams-Beuren syndrome, a rare developmental disorder.

Function:
Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.

Subunit:
Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds to CPLX1. Binds SYTL4 and STXBP6. Found in a ternary complex with STX1A and SNAP25. Interacts with OTOF and LGI3. Interacts with SLC6A4. Interacts with SYT6 and SYT8; the interaction is Ca(2+)-dependent (By similarity). Found in a complex with VAMP8 and SNAP23. Interacts with VAPA and SYBU.xy-11200R    LHX2調(diào)控胚胎干細胞分化蛋白Lhx2抗體
xy-8360R    LRRC2LRRC2蛋白抗體
xy-11090R    LRRC4B神經(jīng)突觸蛋白NGL3抗體
xy-9972R    LCA5L致盲基因LCA5樣蛋白抗體
xy-9973R    LCA5致盲基因LCA5蛋白抗體
xy-7869R    LHX6轉(zhuǎn)錄因子LHX6抗體
xy-7913R    phospho-LATS1+LATS2 (Thr1079 +Thr1041)磷酸化腫瘤抑制基因LATS1/LATS2抗體
xy-11867R    LBX1轉(zhuǎn)錄因子LBX1抗體
xy-11868R    LDB1神經(jīng)細胞特異性轉(zhuǎn)錄因子LDB1抗體
xy-11869R    LECT2白細胞細胞化學(xué)吸引素2抗體
xy-11870R    LHX5LHX5蛋白抗體
xy-11871R    LIM kinase 1 + 2單絲氨酸蛋白激酶1+2抗體
xy-11872R    LIN7CLIN7C蛋白抗體
xy-11873R    LINGO4富含亮氨酸重復(fù)序列Nogo受體反應(yīng)蛋白4抗體
xy-10536R    LRG1富含亮氨酸α2糖蛋白抗體
xy-11875R    LPPR4腦特異性磷脂酸磷酸酶樣蛋白1抗體
xy-11876R    LR8跨膜蛋白TMEM176B抗體
xy-11877R    LRRTM2富含亮氨酸重復(fù)跨膜神經(jīng)元蛋白2抗體
xy-11878R    LRRTM4富含亮氨酸重復(fù)跨膜神經(jīng)元蛋白4抗體
xy-11638R    LZICLZIC蛋白抗體
xy-11879R    LGI3Lgi3蛋白抗體
xy-11880R    Lhx4Lhx4蛋白抗體
xy-11881R    Lunatic Fringe信號轉(zhuǎn)導(dǎo)分子SCDO3抗體
xy-10030R    LEO1RNA聚合酶相關(guān)蛋白LEO1抗體
xy-6946R    LCMV淋巴細胞性脈絡(luò)叢腦膜炎病毒蛋白抗體
xy-11731R    LC3A/B自噬微管相關(guān)蛋白輕鏈3A/3B抗體
xy-10369R    Gonadoliberin-1黃體激素釋放激素/促性腺激素釋放激素抗體
xy-12311R    LRRC23LRRC23蛋白抗體
xy-12312R    LRRC39LRRC39蛋白抗體
xy-8878R    LC3自噬微管相關(guān)蛋白輕鏈3抗體
xy-12342R    L3MBTL3L3MBTL3蛋白抗體
xy-12339R    LRRC25富含亮氨酸重復(fù)蛋白25抗體
xy-2631R    IL-31RA/CRL3白介素31受體a抗體
xy-9387R    LRSAM1LRSAM1蛋白抗體
xy-7336R    Limd1LIM結(jié)構(gòu)域蛋白1抗體