酸性鈣調(diào)蛋白3抗體 返回列表頁(yè)

英文名稱 Acidic Calponin
中文名稱 酸性鈣調(diào)蛋白3抗體
別    名 Acidic calponin 3; acidic isoform; Calponin 3 acidic; Calponin3; Calponin 3; Calponin acidic; Calponin acidic isoform; Calponin; Calponin-3; Calponin3; CNN 3; Cnn3; CNN3_HUMAN; dJ639P13.2.2; OTTHUMP00000012470; OTTHUMP00000012471.
 酸性鈣調(diào)蛋白3抗體    
說(shuō) 明 書 0.2ml  
研究領(lǐng)域 心血管  細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Calponin 3/Acidic Calponin
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
 產(chǎn)品介紹 background:
Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated myosin. Both properties are lost following phosphorylation (primarily at Serine 175) by protein kinase C or calmodulin-dependent protein kinase II. The three forms of Calponin, Calponin 1 (basic Calponin), Calponin 2 (neutral Calponin) and Calponin 3 (acidic Calponin) are found in smooth muscle tissue. Additionally, Calponin 2 is found in heart muscle tissue and Calponin 3 is found in the brain.

Function:
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

Tissue Specificity:
Expressed in both non-smooth muscle tissues as well as smooth muscle tissues.

Similarity:
Belongs to the calponin family.
Contains 3 calponin-like repeats.
Contains 1 CH (calponin-homology) domain.

Database links:

Entrez Gene: 1266 Human

Entrez Gene: 71994 Mouse

Entrez Gene: 54321 Rat

Entrez Gene: 538975 Cow

Omim: 602374 Human

SwissProt: Q32L92 Cow

SwissProt: Q15417 Human

SwissProt: Q9DAW9 Mouse

SwissProt: P37397 Rat

Unigene: 483454 Human

Unigene: 275555 Mouse

Unigene: 57635 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. xy-6821R MAGEB1黑色素瘤相關(guān)抗原B1抗體
xy-2721R MCM5微小染色體維持缺陷蛋白5抗體
xy-4293R MACC1結(jié)腸癌轉(zhuǎn)移相關(guān)蛋白1抗體
xy-4597R MMP-1基質(zhì)金屬蛋白酶-1抗體
xy-5483R phospho-MEF2C(Thr300)磷酸化肌細(xì)胞增強(qiáng)因子2C抗體
xy-5485R Phospho-MEF2A(Thr319)磷酸化肌細(xì)胞增強(qiáng)因子2抗體
xy-5474R phospho-MBP(Thr232)磷酸化髓鞘堿性蛋白抗體
xy-5475R phospho-MBP(Tyr203)磷酸化髓鞘堿性蛋白抗體
xy-5478R phospho-MYL6(Tyr29+Ser30)磷酸化肌球蛋白輕鏈6抗體
xy-5476R phospho-P38 MAPK (Thr180)磷酸化p38MAPK抗體
xy-5477R phospho-p38 MAPK (Tyr323)磷酸化p38MAPK抗體
xy-5480R phospho-MEF2C(Ser396)磷酸化肌細(xì)胞增強(qiáng)因子2C抗體
xy-5487R phospho-MAPK8 ( Thr183 + Tyr185)磷酸化氨基末端激酶2抗體
xy-12201R MELK蛋白激酶MPK38抗體
xy-12206R MGST1微粒體谷胱甘肽S轉(zhuǎn)移酶1抗體
xy-10074R MUC13粘蛋白13抗體
xy-8689R MEPE細(xì)胞外基質(zhì)磷酸化抗體
xy-2725R Mast Cell Tryptase肥大細(xì)胞蛋白酶7抗體
xy-4128R MAP4微管相關(guān)蛋白4抗體
xy-5120R MSS126S蛋白酶調(diào)節(jié)亞型7抗體
xy-3629R MEG1蛋白酪氨酸磷酸酶非受體型4抗體
xy-13355R MBOAT4腦腸肽O酰基轉(zhuǎn)移酶抗體
xy-5272R MRG15轉(zhuǎn)錄調(diào)控因子MRG15抗體
xy-5273R MLL5髓系/淋巴混合譜系白血病蛋白5抗體
xy-4835R MPV17T淋巴細(xì)胞成熟相關(guān)蛋白抗體
xy-9961R cblA甲基丙二酸尿癥cblA抗體
xy-8564R non-muscle Myosin IIA非平滑肌肌球蛋白2A抗體
xy-8671R MMS19DNA修復(fù)甲基磺酸敏感性基因19抗體
xy-9680R C19orf2819號(hào)染色體開(kāi)放閱讀框28抗體
xy-3802R Mammaglobin A乳腺珠蛋白1抗體