TNF家族B細(xì)胞激活因子抗體 返回列表頁(yè)

英文名稱 BAFF
中文名稱 TNF家族B細(xì)胞激活因子抗體
別    名 ApoL related ligand TALL 1; B cell Activating Factor; B lymphocyte stimulator ; BLYS; CD 257; CD257; CD257 antigen; delta BAFF; Dendritic cell derived TNF like molecule; DTL; DTL precursor; TALL 1; TALL1; THANK; TNF and APOL related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; TNF homolog that activates apoptosis NKFB and JNK; TNFSF13B; TNFSF20; Tumor necrosis factor ligand superfamily member 13B; Tumor necrosis factor ligand superfamily member 20; Tumor necrosis factor like protein ZTNF4; Tumor necrosis factor superfamily member 13B; ZTNF4; TN13B_MOUSE .
TNF家族B細(xì)胞激活因子抗體
 
說(shuō) 明 書 0.1ml  0.2ml  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  細(xì)胞凋亡  生長(zhǎng)因子和激素  激酶和磷酸酶  細(xì)胞分化  b-淋巴細(xì)胞  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig, Cow, Rabbit, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
細(xì)胞定位 細(xì)胞膜 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse BAFF
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

產(chǎn)品介紹 background:
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. [provided by RefSeq].

Function:
Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.

Subunit:
Belongs to the tumor necrosis factor family.

Subcellular Location:
Secreted and Cell membrane.

Tissue Specificity:
Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas.

Post-translational modifications:
The soluble form derives from the membrane form by proteolytic processing.
Isoform 2 is not efficiently shed from the membrane unlike isoform 1.

Similarity:
Belongs to the tumor necrosis factor family.

Gene ID:
24099

Database links:

Entrez Gene: 10673 Human

Entrez Gene: 24099 Mouse

Omim: 603969 Human

SwissProt: Q9Y275 Human

SwissProt: Q9WU72 Mouse

Unigene: 525157 Human

Unigene: 596110 Human

Unigene: 28835 Mouse

xy-2668R Bone sialoprotein骨涎蛋白抗體
xy-1488R Bim細(xì)胞死亡調(diào)解子抗體
xy-1489R BIRC6Apollon凋亡抑制蛋白抗體
xy-1628R BONZO細(xì)胞表面趨化因子受體6抗體
xy-1195R beta endorphinβ-內(nèi)啡肽/β endorphin抗體
xy-1509R BMPR1A骨成型蛋白受體1A抗體
xy-1336R Bcl-xLBcl-xL蛋白抗體
xy-1337R phospho-Bcl-xL (Ser62)磷酸化Bcl-xL(Ser62)抗體
xy-1304R Bad相關(guān)死亡促進(jìn)因子Bad抗體
xy-9519R BPGM紅細(xì)胞2,3 - 二磷酸甘油酸合成酶抗體
xy-2229R Brucella布氏桿菌菌體蛋白抗體
xy-3373R phospho-B-Raf (Ser444)磷酸化B-Raf抗體
xy-3374R phospho-B-Raf (Ser602)磷酸化B-Raf抗體
xy-3542R PNK1多聚合苷酸激酶3磷酸化酶抗體
xy-0803R BRCA1乳腺癌易感基因1抗體
xy-1284R BakBcl-2同源拮抗劑抗體
xy-1063R beta 3 Adrenergic Receptorβ3腎上腺素能受體抗體
xy-4865R BNP腦鈉素/利鈉肽抗體
xy-8726R BZW2BZW2蛋白抗體
xy-8675R BDKRB1緩激肽B1受體抗體
xy-4775R BK channel鈣激活鉀通道蛋白α1抗體
xy-11041R Bestrophin 2卵黃狀黃斑病蛋白2抗體
xy-7905R BRSK1絲氨酸/蘇氨酸蛋白激酶SAD-B抗體
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.