骨形態(tài)發(fā)生蛋白6抗體 返回列表頁

英文名稱 BMP6
中文名稱 骨形態(tài)發(fā)生蛋白6抗體
別    名 Bone Morphogenic Protein 6; Decapentaplegic vegetal related; DVR6; BMP 6; BMP-6; TGFB related vegetal related growth factor; Transforming growth factor beta; Vegetal related (TGFB related) cytokine; Vg related sequence; VGR1; BMP6_HUMAN.
骨形態(tài)發(fā)生蛋白6抗體   
說 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  生長因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 
產(chǎn)品應(yīng)用 WB=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 16/56kDa
細(xì)胞定位 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human BMP6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity. [provided by RefSeq].

Function:
Induces cartilage and bone formation.

Subunit:
Interacts with SOSTDC1.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in the lung. Low levels seen in the kidney.

Similarity:
Belongs to the TGF-beta family.

Gene ID:
654

Database links:

Entrez Gene: 654 Human

Entrez Gene: 12161 Mouse

Entrez Gene: 25644 Rat

Omim: 112266 Human

SwissProt: P22004 Human

SwissProt: P20722 Mouse

SwissProt: Q04906 Rat

Unigene: 285671 Human

Unigene: 385759 Mouse

Unigene: 40476 Rat

Important Note:
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