CD44 （CD44） （AA 21-145） 抗體 返回列表頁(yè)

CD44 (CD44) (AA 21-145) 抗體

抗原

CD44 (CD44)
別名 AU023126, AW121933, AW146109, HERMES, Ly-24, Pgp-1, CD44A, METAA, RHAMM, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1
抗原表位
 其他選擇AA 21-145
適用
 其他選擇Human
宿主
 其他選擇Mouse
克隆類型 (克隆位點(diǎn))
單克隆 (5C10)
標(biāo)記
 其他選擇非結(jié)合性
應(yīng)用范圍
 其他選擇Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
[Pubmed] 2 references available
規(guī)格 0.1 mL
發(fā)貨至 中國(guó) (更改)
發(fā)貨時(shí)間 29至35個(gè)工作日

CD44 (CD44) (AA 21-145) 抗體

產(chǎn)品細(xì)節(jié)

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免疫原 Recombinant Human CD44 (aa 21-145) purified from E. coli
克隆位點(diǎn) 5C10
亞型 IgG2b
特異性 This antibody detects Human CD44 / HUTCH-I.
交叉反應(yīng) （詳細(xì)） Species reactivity (tested):Human.
產(chǎn)品特性 Synonyms: CDw44, PGP-I, ECMR-III, Hermes antigen, Epican, LHR, MDU2, MDU3, MIC4, Phagocyticglycoprotein I, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesionreceptor, Hyaluronate receptor, Heparan sulfate proteoglycan
純化方法 Protein-G affinity chromatography

CD44 (CD44) (AA 21-145) 抗體目標(biāo)詳細(xì)情況

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別名 CD44
背景 CD44 is a broadly distributed transmembrane glycoprotein that plays a critical role in a variety of cellular behaviors, including adhesion, migration, invasion, and survival. CD44 mediates cell-cell and cell-matrix interactions in a large part through its affinity for hyaluronan (HA), a glycosaminoglycan constituent of extracellular matrices, but also potentially through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Variants of CD44 are expressed in tissues during development, including embryonic epithelia. Known functions of CD44 are cellular adhesion (aggregation and migration), hyaluronate degradation, lymphocyte activation, lymph node homing, myelopoiesis and lymphopoiesis, angiogenesis, and release of cytokines. The functions of CD44 are principally dependant on cellular adhesion in one setting or another.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1
基因ID 960
UniProt P16070
研究領(lǐng)域 Stem Cells, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells, Cancer, Cell Cycle

使用細(xì)節(jié)

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應(yīng)用備注 ELISA. Western blot: 1/1,000-1/2,000. Immunohistochemistry on Paraffin Sections: 5?μg/mL. 
Other applications not tested. 
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 For Research Use only

CD44 (CD44) (AA 21-145) 抗體貯存及處理

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狀態(tài) Liquid
濃度 1.0 mg/mL
緩沖液 PBS,?pH 7.4, containing 0.09?% Sodium Aziden as preservative.
儲(chǔ)存液 Sodium azide
注意事項(xiàng) This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
儲(chǔ)存條件 4 °C/-20 °C
儲(chǔ)存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
有效期 12 months

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