SMAD Family Member 4 （SMAD4） （Middle Region） 抗體 返回列表頁

SMAD Family Member 4 (SMAD4) (Middle Region) 抗體

抗原
SMAD Family Member 4 (SMAD4)
別名 smad4, DPC4, JIP, MADH4, MYHRS, AW743858, D18Wsu70e, Madh4, XSmad4alpha, Xsmad4, dpc4, jip, madh4, xsmad4a
抗原表位
其他選擇 Middle Region
C-Term(12),AA 56-165 (10),N-Term (8),AA 1-552 (3),pThr277 (3),AA 1-553 (2),AA 400-428 (2),AA 421-520 (2),AA 1-246 (1),AA 188-475 (1),AA 255-284 (1),AA 322-552 (1),AA 323-552 (1),AA 9-231 (1),Middle Region (1),Ser277 (1),Thr277 (1)
適用
其他選擇 Murine, Rat ((Rattus)), Bovine, Pig (Porcine), Human
Human(85),Murine (33),Rat ((Rattus)) (29),Bovine (2),Dog (Canine) (2),Pig (Porcine) (2),Monkey (1),Xenopus laevis (1)
宿主
其他選擇 Rabbit
Rabbit(48),Mouse (34),Goat (7)
克隆類型
多克隆
標記
其他選擇 非結合性
Magnetic Particles(1),Sepharose (1)
應用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(81),ELISA (42),Immunofluorescence (IF) (23),Immunohistochemistry (IHC) (17),Immunocytochemistry (ICC) (11),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (10),Flow Cytometry (FACS) (9),Enzyme Immunoassay (EIA) (7),Immunoprecipitation (IP) (6),Dot Blot (DB) (4),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (3),Immunohistochemistry (Frozen Sections) (IHC (fro)) (2),Proximity Ligation Assay (PLA) (2),Fluorescence Microscopy (FM) (1),Immunoassay (IA) (1)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至12個工作日

SMAD Family Member 4 (SMAD4) (Middle Region) 抗體

產(chǎn)品細節(jié)

顯示 隱藏
免疫原 Synthetic peptide directed towards the middle region of human SMAD4
序列 NIPVASTSQP ASILGGSHSE GLLQIASGPQ PGQNGFTG QPATYHHNST
預測反應 Bovine : 100 %, Goat : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Pig : 100 %, Mouse : 90 %, Rat : 90 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against SMAD4. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Protein A purified

目標詳細情況

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SMAD Family Member 4 (SMAD4) (Middle Region) 抗體目標詳細情況

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別名 SMAD4
背景 SMAD4 is one of the Smad family members, which are essential intracellular signalling components of the transforming growth factor-beta (TGF-beta) superfamily. Smad2 and Smad3 are structurally highly similar and mediate TGF-beta signals. Smad4 is distantly related to Smads 2 and 3, and forms a heteromeric complex with Smad2 after TGF-beta or activin stimulation. TGF-beta induces heteromeric complexes of Smads 2, 3 and 4, and their concomitant translocation to the nucleus, which is required for efficient TGF-beta signal transduction
分子量 60 kDa
基因ID 4089
NCBI Accession NM_005359, NP_005350
UniProt Q13485
研究領域 Signaling, Transcription Factors

使用細節(jié)

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SMAD Family Member 4 (SMAD4) (Middle Region) 抗體使用細節(jié)

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應用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明

Antigen size: 552 AA

限制 For Research Use only

貯存及處理

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貯存及處理

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狀態(tài) Lyophilized
溶解方式 Add 100 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項 Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
儲存方法 For longer periods of storage, store at -20 °C

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