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抗原
ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B)
別名 apg4b, APG4B, AUTL1, 2510009N07Rik, AW048066, Apg4b, Atg4bl, Autl1, Aut2b2
抗原表位
其他選擇 C-Term
Internal Region(15),AA 264-293 (8),N-Term (8),AA 239-265 (7),C-Term (5),AA 16-45 (2),AA 23-53 (2),AA 258-284 (2),AA 350-400 (2),AA 1-211 (1),AA 1-30 (1),AA 126-372 (1),AA 20-80 (1),AA 250-290 (1),AA 275-325 (1),AA 358-390 (1),AA 364-393 (1),AA 71-120 (1),Center (1)
適用
其他選擇 Murine, Rat ((Rattus)), Dog (Canine), Human
Human(79),Murine (34),Rat ((Rattus)) (16),Bovine (14),Dog (Canine) (13),Chicken (3),Pig (Porcine) (2),Xenopus laevis (2),Zebrafish (Danio rerio) (2),Fish (1),Mammalian (1)
宿主
其他選擇 Rabbit
Rabbit(76),Mouse (3),Sheep (1)
克隆類型
多克隆
標記
其他選擇 非結(jié)合性
Biotin(3),FITC (3),HRP (3),APC (2),Alkaline Phosphatase (AP) (2),PE (2),Alexa Fluor 350 (1),Alexa Fluor 488 (1),Alexa Fluor 555 (1),Alexa Fluor 647 (1),Cy3 (1),Cy5 (1),Cy5.5 (1),Cy7 (1)
應用范圍
其他選擇 Western Blotting (WB)
Western Blotting (WB)(67),Immunohistochemistry (IHC) (32),ELISA (26),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (14),Immunofluorescence (Paraffin-embedded Sections) (IF (p)) (10),Dot Blot (DB) (2),Enzyme Immunoassay (EIA) (2),Immunofluorescence (IF) (2),Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)) (2),Immunoprecipitation (IP) (2),Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
[Pubmed] 1 reference available
規(guī)格 100 μg
發(fā)貨至 中國 (更改)
發(fā)貨時間 9至12個工作日
ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) (C-Term) 抗體
產(chǎn)品細節(jié)
顯示 隱藏
免疫原 Synthetic peptide directed towards the C terminal of human ATG4B
序列 LGGALPMFEL VELQPSHLAC PDVLNLSLDS SDVERLERFF DSEDEDFEIL
預測反應 Zebrafish :84 %, Bovine :94 %, Human :104 %, Mouse :104 %, African clawed frog :74 %, Chicken :84 %
產(chǎn)品特性 This is a rabbit polyclonal antibody against ATG4B. It was validated on Western Blot using a cell lysate as a positive control.
純化方法 Protein A purified
目標詳細情況
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ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) (C-Term) 抗體目標詳細情況
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別名 ATG4B
背景 Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
分子量 44 kDa
基因ID 23192
NCBI Accession NP_037457, NM_013325
UniProt Q9Y4P1
研究領(lǐng)域 Cancer, Autophagy, Proteolysis / Ubiquitin
使用細節(jié)
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ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) (C-Term) 抗體使用細節(jié)
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應用備注 Optimal working dilutions should be determined experimentally by the investigator.
說明
Antigen size: 393 AA
限制 For Research Use only
貯存及處理
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貯存及處理
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狀態(tài) Lyophilized
溶解方式 Add 100 µL of distilled water.
濃度 1 mg/mL
緩沖液 PBS buffer with 2 % sucrose
注意事項 Avoid repeated freeze-thaw cycles.
儲存條件 -20 °C
儲存方法 For longer periods of storage, store at -20 °C
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